Protein: GRIA2
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)

Gene: GRIA2
Organism: Homo sapiens
Interactions: 56
UniProt ID: P42262

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

838442

GRIA1
Glutamate receptor 1

4

18

Small-scale

0.873

High

838477

GRIA2
Glutamate receptor 2

3

18

Small-scale

0.834

High

838510

PICK1
PRKCA-binding protein

8

11

Small-scale

0.752

High

838517

GRIP1
Glutamate receptor-interacting protein 1

5

20

Small-scale

0.707

High

838479

NSF
Vesicle-fusing ATPase

3

4

Small-scale

0.678

High

215876

GRID2
Glutamate receptor ionotropic, delta-2

1

18

Small-scale

0.618

High

838478

GRIA3
Glutamate receptor 3

1

18

Small-scale

0.618

High

838490

GRIK2
Glutamate receptor ionotropic, kainate 2

1

18

Small-scale

0.618

High

838512

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

18

Small-scale

0.618

High

838519

CCG2
Voltage-dependent calcium channel gamma-2 subunit

1

15

Small-scale

0.618

High

408714

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

Small-scale

0.561

High

424017

ITB3
Integrin beta-3

1

2

Small-scale

0.561

High

835570

TSN7
Tetraspanin-7

1

1

Small-scale

0.561

High

838483

CDC42
Cell division control protein 42 homolog

1

2

Small-scale

0.561

High

838494

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

10

Small-scale

0.561

High

838495

SRC8
Src substrate cortactin

1

10

Small-scale

0.561

High

838509

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.561

High

838508

RN167
E3 ubiquitin-protein ligase RNF167

1

0

Small-scale

0.554

High

838492

KCAB2
Voltage-gated potassium channel subunit beta-2

1

1

High-throughput

0.536

High

838481

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

140165

SDCB1
Syntenin-1

1

20

Small-scale

0.501

High

838480

GSK3B
Glycogen synthase kinase-3 beta

1

2

Small-scale

0.501

High

838485

RAC1
Ras-related C3 botulinum toxin substrate 1

1

2

Small-scale

0.501

High

838488

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

9

Small-scale

0.501

High

838505

SYT3
Synaptotagmin-3

1

1

Small-scale

0.501

High

838503

P121A
Nuclear envelope pore membrane protein POM 121

1

6

High-throughput

0.489

High

431741

ITB1
Integrin beta-1

1

3

Small-scale

0.479

High

838484

RB11A
Ras-related protein Rab-11A

1

2

Small-scale

0.479

High

838486

DLG4
Disks large homolog 4

1

20

Small-scale

0.479

High

838489

TROP
Trophinin

1

3

High-throughput

0.479

High

838498

RN220
E3 ubiquitin-protein ligase RNF220

1

4

Small-scale

0.479

High

838499

PHLB2
Pleckstrin homology-like domain family B member 2

1

7

Small-scale

0.479

High

838506

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

5

Small-scale

0.479

High

838515

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

7

Small-scale

0.479

High

838516

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

5

Small-scale

0.479

High

105500

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

665541

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

1

High-throughput

0.437

High

838493

NCOA4
Nuclear receptor coactivator 4

1

1

High-throughput

0.437

High

838501

NEK9
Serine/threonine-protein kinase Nek9

1

2

High-throughput

0.437

High

838504

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

6

Small-scale

0.437

High

838518

MYO5A
Unconventional myosin-Va

1

4

Small-scale

0.437

High

76601

B4DZ85
Nuclear receptor coactivator 4

1

1

High-throughput

0.407

High

838497

Q5QNZ2
ATP synthase subunit b

1

1

High-throughput

0.407

High

838496

DGUOK
Deoxyguanosine kinase, mitochondrial

3

0

High-throughput

0.347

High

838511

KTU
Protein kintoun

3

0

High-throughput

0.347

High

838513

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

124258

HAX1
HCLS1-associated protein X-1

2

0

High-throughput

0.318

High

838502

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.282

High

351085

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.279

Low

838482

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

0

High-throughput

0.279

Low

838487

TXN4A
Thioredoxin-like protein 4A

1

0

High-throughput

0.279

Low

838500

DPP9
Dipeptidyl peptidase 9

1

0

High-throughput

0.279

Low

838507

TSYL2
Testis-specific Y-encoded-like protein 2

1

0

High-throughput

0.279

Low

838514

TRM6
tRNA

1

0

High-throughput

0.279

Low

838491

REST
RE1-silencing transcription factor

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025