Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: CARL1 (Q5VZK9)
F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein regulator and myosin 1 linker protein 1) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (Leucine-rich repeat-containing protein 16A)
Gene: CARMIL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CARMIL_C~F_actin_cap_B
Common GO terms GO:0005829 - cytosol
GO:0030027 - lamellipodium
GO:0030032 - lamellipodium assembly
GO:0070062 - extracellular exosome
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 272
Hs

1 1371
+ Dm
+ Hs
+ Mm

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Last updated: 15 Jul 2024