HitPredict

Interactor 1: XCL1 (P47992)
Lymphotactin (ATAC) (C motif chemokine 1) (Cytokine SCM-1) (Lymphotaxin) (SCM-1-alpha) (Small-inducible cytokine C1) (XC chemokine ligand 1)
Gene: XCL1

Interactor 2: CXL17 (Q6UXB2)
C-X-C motif chemokine 17 (6-Cys CXCL17) (Dendritic cell and monocyte chemokine-like protein) (DMC) (VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17]
Gene: CXCL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 114 Hs			1 119
+	Hs
		1166409 XCL2_HUMAN (1-114): 2.95e-42: 136: 98.25		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166407 CCL13_HUMAN (2-92): 8.96e-33: 112: 25.81		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		945620 CCL8_HUMAN (13-93): 7.25e-31: 107: 28.57		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		528221 CCL2_HUMAN (13-92): 1.14e-26: 96.2: 24.10		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		528267 CCL5_HUMAN (11-86): 2.34e-22: 85.1: 26.92		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		944668 CCL20_HUMAN (6-91): 9.71e-22: 83.9: 28.89		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166406 CCL17_HUMAN (1-85): 1.23e-21: 83.5: 24.14		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		179467 CCL25_HUMAN (4-89): 5.99e-20: 80.8: 19.15		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		1166410 CCL26_HUMAN (24-89): 4.6e-20: 79.3: 32.35		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00
+	Hs
		134308 CCL21_HUMAN (22-93): 4.24e-19: 78.1: 20.51		CXL17_HUMAN (1-119): 5.21e-77: 224: 100.00