Protein: FBXW4
F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)

Gene: FBXW4
Organism: Homo sapiens
Interactions: 58
UniProt ID: P57775

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016055 - Wnt signaling pathway
GO:0019005 - SCF ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

885030

SKP1
S-phase kinase-associated protein 1

6

20

Small-scale

0.943

High

885038

CUL1
Cullin-1

6

20

Small-scale

0.935

High

885037

PHLP
Phosducin-like protein

3

9

High-throughput

0.861

High

885058

PDCL3
Phosducin-like protein 3

3

9

High-throughput

0.861

High

573190

TCPA
T-complex protein 1 subunit alpha

4

20

Small-scale

0.694

High

821142

TCPE
T-complex protein 1 subunit epsilon

4

20

Small-scale

0.694

High

826588

TCPG
T-complex protein 1 subunit gamma

4

20

Small-scale

0.694

High

842802

TCPQ
T-complex protein 1 subunit theta

4

20

Small-scale

0.694

High

843127

TCPD
T-complex protein 1 subunit delta

4

20

Small-scale

0.694

High

885031

TCPB
T-complex protein 1 subunit beta

4

20

Small-scale

0.694

High

885053

TCPH
T-complex protein 1 subunit eta

4

20

Small-scale

0.694

High

147231

TXND9
Thioredoxin domain-containing protein 9

3

9

High-throughput

0.667

High

770759

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.667

High

885047

TCPW
T-complex protein 1 subunit zeta-2

3

20

High-throughput

0.667

High

227006

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.665

High

885041

SKI2
Superkiller complex protein 2

1

20

Small-scale

0.618

High

885051

PFD5
Prefoldin subunit 5

2

7

High-throughput

0.611

High

885060

PDRG1
p53 and DNA damage-regulated protein 1

3

1

High-throughput

0.609

High

885046

CSN6
COP9 signalosome complex subunit 6

2

4

Small-scale

0.571

High

885039

CUL4A
Cullin-4A

1

20

High-throughput

0.553

High

885042

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.541

High

885064

PFD2
Prefoldin subunit 2

1

5

High-throughput

0.536

High

885054

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.518

High

885056

RNF32
RING finger protein 32

1

0

High-throughput

0.518

High

885067

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

14

High-throughput

0.494

High

885043

ANR39
Ankyrin repeat domain-containing protein 39

1

16

High-throughput

0.489

High

885045

SPT6H
Transcription elongation factor SPT6

1

6

High-throughput

0.489

High

571375

DDX5
Probable ATP-dependent RNA helicase DDX5

1

15

Small-scale

0.479

High

637661

PSA2
Proteasome subunit alpha type-2

1

6

Small-scale

0.479

High

672058

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

9

Small-scale

0.479

High

672393

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

9

Small-scale

0.479

High

885029

CSN2
COP9 signalosome complex subunit 2

1

7

Small-scale

0.479

High

885033

1433F
14-3-3 protein eta

1

20

Small-scale

0.479

High

885034

DHX9
ATP-dependent RNA helicase A

1

16

Small-scale

0.479

High

885035

CSN1
COP9 signalosome complex subunit 1

1

6

Small-scale

0.479

High

885036

REST
RE1-silencing transcription factor

1

4

Small-scale

0.479

High

885040

DCTN1
Dynactin subunit 1

1

14

Small-scale

0.479

High

885048

NU205
Nuclear pore complex protein Nup205

1

1

Small-scale

0.479

High

885049

CSN5
COP9 signalosome complex subunit 5

1

6

Small-scale

0.479

High

885055

CSN4
COP9 signalosome complex subunit 4

1

2

Small-scale

0.479

High

885057

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

885059

CSN7B
COP9 signalosome complex subunit 7b

1

5

Small-scale

0.479

High

885061

NLK
Serine/threonine-protein kinase NLK

1

8

Small-scale

0.479

High

885062

CSN7A
COP9 signalosome complex subunit 7a

1

5

Small-scale

0.479

High

885063

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

885065

CSN3
COP9 signalosome complex subunit 3

1

7

Small-scale

0.479

High

885066

RUVB1
RuvB-like 1

1

4

Small-scale

0.479

High

885052

CSN8
COP9 signalosome complex subunit 8

1

0

Small-scale

0.458

High

344465

A2MG
Alpha-2-macroglobulin

1

2

High-throughput

0.439

High

202105

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

13

Small-scale

0.437

High

245955

PFD1
Prefoldin subunit 1

1

6

Small-scale

0.437

High

279107

ATP5H
ATP synthase subunit d, mitochondrial

1

2

Small-scale

0.437

High

708408

MCM4
DNA replication licensing factor MCM4

1

8

Small-scale

0.437

High

865102

RCAN1
Calcipressin-1

1

2

Small-scale

0.437

High

885032

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

9

Small-scale

0.437

High

885050

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

885044

SLX4I
Protein SLX4IP

1

0

High-throughput

0.279

Low

380989

SEMG1
Semenogelin-1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024