Protein: PSME2
Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta)

Gene: PSME2
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q9UL46

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008537 - proteasome activator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

986867

PSME1
Proteasome activator complex subunit 1

11

4

Small-scale

0.978

High

656140

PSB9
Proteasome subunit beta type-9

5

20

Small-scale

0.927

High

1356773

PSME2
Proteasome activator complex subunit 2

4

4

Small-scale

0.902

High

637601

PSA1
Proteasome subunit alpha type-1

4

16

High-throughput

0.895

High

1303494

PSB7
Proteasome subunit beta type-7

4

19

Small-scale

0.895

High

832175

PSB2
Proteasome subunit beta type-2

4

20

Small-scale

0.892

High

594658

PSB1
Proteasome subunit beta type-1

3

20

High-throughput

0.871

High

637753

PSA2
Proteasome subunit alpha type-2

3

18

Small-scale

0.861

High

656542

PSB4
Proteasome subunit beta type-4

3

20

High-throughput

0.861

High

656335

PSA5
Proteasome subunit alpha type-5

2

15

High-throughput

0.811

High

832056

PSB3
Proteasome subunit beta type-3

2

20

High-throughput

0.811

High

656084

PSB8
Proteasome subunit beta type-8

2

20

Small-scale

0.789

High

638215

PSA4
Proteasome subunit alpha type-4

2

19

Small-scale

0.754

High

156373

PSA7
Proteasome subunit alpha type-7

1

16

High-throughput

0.691

High

133066

SDCB1
Syntenin-1

4

0

High-throughput

0.669

High

529899

CFTR
Cystic fibrosis transmembrane conductance regulator

3

1

High-throughput

0.643

High

131104

PSDE
26S proteasome non-ATPase regulatory subunit 14

3

2

Small-scale

0.640

High

1300123

CDK15
Cyclin-dependent kinase 15

2

1

High-throughput

0.628

High

1356776

FBX7
F-box only protein 7

2

2

High-throughput

0.628

High

638039

PSA3
Proteasome subunit alpha type-3

1

14

Small-scale

0.618

High

656659

PSB6
Proteasome subunit beta type-6

1

20

Small-scale

0.618

High

771479

PSB10
Proteasome subunit beta type-10

1

20

Small-scale

0.618

High

1062894

PSMD6
26S proteasome non-ATPase regulatory subunit 6

2

1

Small-scale

0.611

High

771514

CTRL
Chymotrypsin-like protease CTRL-1

3

1

High-throughput

0.609

High

1252547

LNX1
E3 ubiquitin-protein ligase LNX

2

3

High-throughput

0.606

High

1313942

DUS23
Dual specificity protein phosphatase 23

2

5

High-throughput

0.606

High

361947

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.602

High

1165268

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

2

0

High-throughput

0.602

High

1253922

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

782308

NAA10
N-alpha-acetyltransferase 10

1

1

Small-scale

0.586

High

1318207

UBL5
Ubiquitin-like protein 5

2

0

High-throughput

0.580

High

108954

H0YKT8
Proteasome subunit beta

1

19

High-throughput

0.575

High

1316182

RNF26
E3 ubiquitin-protein ligase RNF26

2

2

High-throughput

0.574

High

261155

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

893619

SEM1
26S proteasome complex subunit SEM1

1

2

Small-scale

0.536

High

897195

TM258
Transmembrane protein 258

1

1

High-throughput

0.536

High

1085541

MK06
Mitogen-activated protein kinase 6

1

2

High-throughput

0.536

High

1282456

PSMG2
Proteasome assembly chaperone 2

1

2

High-throughput

0.536

High

1305850

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

546054

MYOD1
Myoblast determination protein 1

1

0

High-throughput

0.518

High

336618

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

565987

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

882834

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

958789

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

1349067

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.513

High

396030

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

665359

EPHA2
Ephrin type-A receptor 2

1

1

High-throughput

0.494

High

816668

CXA8
Gap junction alpha-8 protein

1

3

High-throughput

0.489

High

1356779

CXA3
Gap junction alpha-3 protein

1

3

High-throughput

0.489

High

125784

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

126179

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

1

Small-scale

0.479

High

229037

PRKN
E3 ubiquitin-protein ligase parkin

1

3

Small-scale

0.479

High

245080

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

295388

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

324680

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

497776

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.479

High

504939

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

562588

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.479

High

573106

PRS6A
26S proteasome regulatory subunit 6A

1

7

High-throughput

0.479

High

610531

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.479

High

641978

U2AF2
Splicing factor U2AF 65 kDa subunit

1

4

High-throughput

0.479

High

780308

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

832775

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

903596

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.479

High

1050296

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

1064828

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1139131

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

1148864

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

1172225

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1200747

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1256917

PARD3
Partitioning defective 3 homolog

1

3

Small-scale

0.479

High

1266893

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

1344532

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

Small-scale

0.479

High

1347312

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

1354824

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1356774

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

1356777

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

4

Small-scale

0.479

High

149410

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

206152

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

560425

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

673113

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

725713

ACTN2
Alpha-actinin-2

1

0

High-throughput

0.458

High

922459

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

1056163

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1085372

FSCN1
Fascin

1

0

High-throughput

0.458

High

1159332

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1217121

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.458

High

1284269

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1356778

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.458

High

92629

E9PMD8
Proteasome 26S subunit, ATPase 3

1

6

High-throughput

0.445

High

1318893

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

385703

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

1356775

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

831785

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.408

High

263972

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

571246

EGLN
Endoglin

1

0

High-throughput

0.279

Low

971828

HEN1
Helix-loop-helix protein 1

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024