HitPredict

Interactor 1: RSP5 (P39940)
E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
Gene: RSP5

Interactor 2: EAR1 (Q03212)
Protein EAR1 (Endosomal adapter of RSP5)
Gene: EAR1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.708

The method score is based on:

Property Details
Experiments 26508657, 17551511, 20489023, 16606443, 18367543
Identification Methods affinity chromatography technology, enzymatic study, unspecified method, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0010008 - endosome membrane
GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 809
Sc

1 550
+ Sc
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 11Aug2025