HitPredict

Interactor 1: GRIA4 (P48058)
Glutamate receptor 4 (GluR-4) (GluR4) (AMPA-selective glutamate receptor 4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4)
Gene: GRIA4

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11891216
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 902 Hs			1 1128
+	Rn
		585210 GRIA4_RAT (1-902): 0: 916: 98.23		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Hs
		786717 GRIA1_HUMAN (4-901): 0: 861: 66.16		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786768 GRIA3_HUMAN (2-862): 0: 843: 73.41		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		786750 GRIA2_HUMAN (1-849): 0: 825: 73.42		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Rn
		585145 GRIA1_RAT (4-901): 0: 858: 65.97		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585193 GRIA3_RAT (2-862): 0: 840: 72.95		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585169 GRIA2_RAT (1-849): 0: 824: 73.30		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		585198 GRIA3_RAT (2-862): 0: 840: 72.95		GRIP2_RAT (1-1105): 6.49e-159: 501: 56.63
+	Rn
		585187 GRIA2_RAT (1-849): 0: 824: 73.30		GRIP2_RAT (1-1105): 6.49e-159: 501: 56.63
+	Mm
		1143565 GRIA4_MOUSE (1-902): 0: 920: 99.67		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		786696 GRIA1_HUMAN (4-901): 0: 861: 66.16		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Mm
		620904 GRIA1_MOUSE (4-901): 0: 858: 66.41		DLG2_MOUSE (998-1124): 1.41e-15: 84: 18.57
+	Rn
		585151 GRIA1_RAT (4-901): 0: 858: 65.97		DLG1_RAT (9-377): 2.47e-15: 83.2: 13.98
+	Mm
		620881 GRIA1_MOUSE (4-901): 0: 858: 66.41		DLG3_MOUSE (792-1120): 2.61e-15: 83.2: 13.99
+	Rn
		585138 GRIA1_RAT (4-901): 0: 858: 65.97		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		620892 GRIA1_MOUSE (4-901): 0: 858: 66.41		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Mm
		1143566 GRIA3_MOUSE (2-862): 0: 845: 73.99		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		786757 GRIA3_HUMAN (2-862): 0: 843: 73.41		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Hs
		786726 GRIA2_HUMAN (1-849): 0: 825: 73.42		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Mm
		620965 GRIA2_MOUSE (1-849): 0: 824: 73.30		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74