HitPredict

Interactor 1: LIMS1 (P48059)
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48)
Gene: LIMS1

Interactor 2: PARVA (Q9NVD7)
Alpha-parvin (Actopaxin) (CH-ILKBP) (Calponin-like integrin-linked kinase-binding protein) (Matrix-remodeling-associated protein 2)
Gene: PARVA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	11331308, 26186194, 28514442, 33961781, 12432066
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 372
+	Mm
		1307770 LIMS1_MOUSE (1-325): 3.81e-88: 268: 99.39		PARVA_MOUSE (1-372): 0: 569: 98.39
+	Hs
		1190450 LIMS2_HUMAN (1-325): 9.68e-87: 265: 85.54		PARVA_HUMAN (1-372): 0: 571: 100.00
+	Hs
		816281 LIMS1_HUMAN (1-325): 4.68e-88: 268: 100.00		PARVB_HUMAN (23-372): 0: 551: 75.71
+	Hs
		823501 PAXI_HUMAN (190-318): 4.32e-39: 147: 37.98		PARVA_HUMAN (1-372): 0: 571: 100.00
+	Hs
		238995 LPXN_HUMAN (190-317): 3.59e-33: 127: 35.16		PARVA_HUMAN (1-372): 0: 571: 100.00
+	Hs
		816280 LIMS1_HUMAN (1-325): 4.68e-88: 268: 100.00		PARVG_HUMAN (69-368): 1.36e-145: 417: 43.00
+	Ce
		184095 UNC97_CAEEL (1-318): 3.11e-81: 251: 60.82		PARV_CAEEL (13-371): 2.2e-151: 433: 46.28
+	Dm
		1213626 Q8INQ9_DROME (3-124): 2.88e-21: 94.7: 28.46		Q9VWD0_DROME (12-370): 0: 519: 57.78
+	Hs
		1335458 PDLI7_HUMAN (191-324): 1.12e-35: 135: 29.85		PARVG_HUMAN (69-368): 1.36e-145: 417: 43.00