HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 342
+	Hs
		818094 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		817977 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Mm
		1141956 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		RBBP7_MOUSE (10-342): 1.03e-68: 222: 14.51
+	Mm
		1141928 Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24		RBBP4_MOUSE (10-342): 2.39e-68: 221: 13.98
+	Mm
		818712 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		RBBP4_MOUSE (10-342): 2.39e-68: 221: 13.98
+	Hs
		727716 SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		881789 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		903001 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		1083400 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		997917 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		997919 TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		817868 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		1083355 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		997865 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		996629 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		1288324 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		996824 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		903450 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		903169 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		996930 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05