Protein: SWE1
Mitosis inhibitor protein kinase SWE1 (EC 2.7.11.1) (Wee1 homolog)

Gene: SWE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 165
UniProt ID: P32944

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000320 - re-entry into mitotic cell cycle
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

339543

CDK1
Cyclin-dependent kinase 1

9

19

Small-scale

0.980

High

624678

CG22
G2/mitotic-specific cyclin-2

6

11

Small-scale

0.948

High

693089

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

6

19

Small-scale

0.945

High

594119

CKS1
Cyclin-dependent kinases regulatory subunit

2

3

Small-scale

0.799

High

701922

CDC14
Tyrosine-protein phosphatase CDC14

2

6

Small-scale

0.789

High

366039

HSP82
ATP-dependent molecular chaperone HSP82

2

20

Small-scale

0.768

High

701859

HSL7
Protein arginine N-methyltransferase HSL7

7

1

Small-scale

0.755

High

416770

CDC31
Cell division control protein 31

1

5

High-throughput

0.691

High

420259

CALM
Calmodulin

1

3

High-throughput

0.691

High

526135

KIN1
Serine/threonine protein kinase KIN1

1

20

High-throughput

0.691

High

526208

KIN2
Serine/threonine-protein kinase KIN2

1

20

High-throughput

0.691

High

584689

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.691

High

701893

CSK2B
Casein kinase II subunit beta

1

8

High-throughput

0.691

High

701907

MLC1
Myosin light chain 1

1

3

High-throughput

0.691

High

630989

KCC4
Probable serine/threonine-protein kinase KCC4

1

20

Small-scale

0.681

High

350766

RAS1
Ras-like protein 1

1

20

High-throughput

0.647

High

477611

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

11

High-throughput

0.647

High

648355

NSR1
Nuclear localization sequence-binding protein

1

15

High-throughput

0.647

High

701848

EDE1
EH domain-containing and endocytosis protein 1

1

20

High-throughput

0.647

High

701857

YPT10
GTP-binding protein YPT10

1

10

High-throughput

0.647

High

701863

RIM4
Meiotic activator RIM4

1

14

High-throughput

0.647

High

701901

CLA4
Serine/threonine-protein kinase CLA4

1

19

Small-scale

0.647

High

701906

MIG2
Regulatory protein MIG2

1

8

High-throughput

0.647

High

701916

JJJ1
J protein JJJ1

1

20

High-throughput

0.647

High

701920

CRZ1
Transcriptional regulator CRZ1

1

7

High-throughput

0.647

High

701926

GAL83
SNF1 protein kinase subunit beta-3

1

1

High-throughput

0.647

High

701946

ENV7
Serine/threonine-protein kinase ENV7

1

17

High-throughput

0.647

High

701953

ARP8
Actin-like protein ARP8

1

11

High-throughput

0.647

High

701871

KEL1
Kelch repeat-containing protein 1

2

10

High-throughput

0.628

High

605618

KIN3
Serine/threonine-protein kinase KIN3

1

20

High-throughput

0.621

High

687867

NUD1
Protein NUD1

1

20

Small-scale

0.621

High

701867

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

4

High-throughput

0.621

High

618761

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

2

20

Small-scale

0.619

High

618824

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

2

20

Small-scale

0.619

High

649944

BUD14
Bud site selection protein 14

2

2

High-throughput

0.619

High

701854

SPC42
Spindle pole body component SPC42

2

1

High-throughput

0.619

High

443927

CYAA
Adenylate cyclase

1

20

High-throughput

0.618

High

543457

HSC82
ATP-dependent molecular chaperone HSC82

1

20

Small-scale

0.618

High

701899

BUD4
Bud site selection protein 4

1

0

High-throughput

0.614

High

539457

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

2

5

Small-scale

0.602

High

509414

CDC24
Cell division control protein 24

2

19

High-throughput

0.590

High

666244

BEM1
Bud emergence protein 1

2

20

High-throughput

0.590

High

620010

MPIP
M-phase inducer phosphatase

1

0

Small-scale

0.586

High

701939

DIB1
Spliceosomal protein DIB1

2

0

High-throughput

0.579

High

541656

SEC63
Protein translocation protein SEC63

1

4

High-throughput

0.579

High

355424

H2B1
Histone H2B.1

1

20

Small-scale

0.561

High

585285

MYO2
Myosin-2

1

13

High-throughput

0.536

High

689230

SP110
Spindle pole body component 110

1

20

High-throughput

0.536

High

696284

PP12
Serine/threonine-protein phosphatase PP1-2

1

13

High-throughput

0.536

High

701902

KEL2
Kelch repeat-containing protein 2

1

10

High-throughput

0.536

High

701903

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

12

High-throughput

0.536

High

701875

MET30
F-box protein MET30

1

16

Small-scale

0.515

High

701845

SPC29
Spindle pole component 29

1

0

High-throughput

0.513

High

701883

PEP8
Carboxypeptidase Y-deficient protein 8

1

0

High-throughput

0.513

High

701954

AHC1
Protein AHC1

1

0

High-throughput

0.513

High

343285

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

7

High-throughput

0.501

High

498861

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.501

High

514544

BIK1
Nuclear fusion protein BIK1

1

13

High-throughput

0.501

High

562208

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

8

High-throughput

0.501

High

562350

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

8

High-throughput

0.501

High

563943

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.501

High

579853

DDR48
Stress protein DDR48

1

1

High-throughput

0.501

High

621163

FPS1
Glycerol uptake/efflux facilitator protein

1

3

High-throughput

0.501

High

625969

PTP1
Tyrosine-protein phosphatase 1

1

9

High-throughput

0.501

High

657128

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

10

High-throughput

0.501

High

693428

PAH1
Phosphatidic acid phosphohydrolase 1

1

4

High-throughput

0.501

High

698197

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

9

High-throughput

0.501

High

699657

DRS1
ATP-dependent RNA helicase DRS1

1

14

High-throughput

0.501

High

699773

KPR1
Ribose-phosphate pyrophosphokinase 1

1

10

High-throughput

0.501

High

701850

SKT5
Chitin synthase regulator SKT5

1

3

High-throughput

0.501

High

701853

ELF1
Transcription elongation factor 1

1

1

High-throughput

0.501

High

701861

LEO1
RNA polymerase-associated protein LEO1

1

1

High-throughput

0.501

High

701862

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

17

High-throughput

0.501

High

701866

YNG2
Chromatin modification-related protein YNG2

1

1

High-throughput

0.501

High

701872

YHY2
Uncharacterized protein YHR182W

1

2

High-throughput

0.501

High

701878

YAT2
Carnitine O-acetyltransferase YAT2

1

3

High-throughput

0.501

High

701884

6P21
6-phosphofructo-2-kinase 1

1

9

High-throughput

0.501

High

701892

IRC5
Uncharacterized ATP-dependent helicase IRC5

1

2

High-throughput

0.501

High

701896

ARC1
tRNA-aminoacylation cofactor ARC1

1

1

High-throughput

0.501

High

701897

ALY2
Arrestin-related trafficking adapter 3

1

4

High-throughput

0.501

High

701904

SKP1
Suppressor of kinetochore protein 1

1

2

High-throughput

0.501

High

701912

GYP2
GTPase-activating protein GYP2

1

4

High-throughput

0.501

High

701917

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

13

High-throughput

0.501

High

701921

SUB1
RNA polymerase II transcriptional coactivator SUB1

1

2

High-throughput

0.501

High

701925

ERB1
Ribosome biogenesis protein ERB1

1

8

High-throughput

0.501

High

701930

KYNU
Kynureninase

1

1

High-throughput

0.501

High

701933

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.501

High

701940

BDF2
Bromodomain-containing factor 2

1

15

High-throughput

0.501

High

701944

AB140
tRNA(Thr)

1

1

High-throughput

0.501

High

701945

CTI6
Histone deacetylase complex subunit CTI6

1

1

High-throughput

0.501

High

701951

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.493

High

701864

VPS29
Vacuolar protein sorting-associated protein 29

1

1

High-throughput

0.489

High

701914

COPA
Coatomer subunit alpha

1

7

High-throughput

0.489

High

701851

CASP
Protein CASP

1

20

High-throughput

0.481

High

701876

MBO1
Gamma tubulin complex adapter SPC72

1

1

High-throughput

0.481

High

701888

SPR3
Sporulation-regulated protein 3

1

1

High-throughput

0.481

High

701934

NDE1
Nuclear distribution protein nudE homolog 1

1

1

High-throughput

0.481

High

701947

NOP53
Ribosome biogenesis protein NOP53

1

3

High-throughput

0.481

High

439709

MET2
Homoserine O-acetyltransferase

1

0

High-throughput

0.480

High

701855

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.480

High

701856

RNZ
Ribonuclease Z

1

0

High-throughput

0.480

High

701860

SWC5
SWR1-complex protein 5

1

0

High-throughput

0.480

High

701868

NSG1
Protein NSG1

1

0

High-throughput

0.480

High

701869

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.480

High

701870

LIN1
Protein LIN1

1

0

High-throughput

0.480

High

701873

SPT8
Transcription factor SPT8

1

0

High-throughput

0.480

High

701879

YEQ9
Uncharacterized protein YER079W

1

0

High-throughput

0.480

High

701880

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

0

High-throughput

0.480

High

701881

VID27
Vacuolar import and degradation protein 27

1

0

High-throughput

0.480

High

701882

RT106
Histone chaperone RTT106

1

0

High-throughput

0.480

High

701885

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.480

High

701890

ECO1
N-acetyltransferase ECO1

1

0

Small-scale

0.480

High

701895

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.480

High

701898

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.480

High

701909

SDS23
Protein SDS23

1

0

High-throughput

0.480

High

701910

YG1B
Uncharacterized protein YGR017W

1

0

High-throughput

0.480

High

701915

TR112
Multifunctional methyltransferase subunit TRM112

1

0

High-throughput

0.480

High

701924

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.480

High

701928

SVF1
Ceramide-binding protein SVF1

1

0

High-throughput

0.480

High

701929

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.480

High

701932

LOA1
Lysophosphatidic acid:oleoyl-CoA acyltransferase 1

1

0

High-throughput

0.480

High

701937

UBX5
UBX domain-containing protein 5

1

0

High-throughput

0.480

High

701941

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.480

High

701950

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.480

High

701952

HIF1
HAT1-interacting factor 1

1

0

High-throughput

0.480

High

701844

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

701935

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

528320

CAPZB
F-actin-capping protein subunit beta

1

6

High-throughput

0.457

High

572031

CLC1
Clathrin light chain

1

1

High-throughput

0.457

High

687600

DGR2
2-deoxy-glucose resistant protein 2

1

11

High-throughput

0.457

High

692730

SPT16
FACT complex subunit SPT16

1

6

High-throughput

0.457

High

693837

SRP40
Suppressor protein SRP40

1

4

High-throughput

0.457

High

697786

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

1

High-throughput

0.457

High

701849

PTH2
Peptidyl-tRNA hydrolase 2

1

1

High-throughput

0.457

High

701874

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.457

High

701887

AIM21
Altered inheritance of mitochondria protein 21

1

3

High-throughput

0.457

High

701889

ATG18
Autophagy-related protein 18

1

9

High-throughput

0.457

High

701894

MTHR1
Methylenetetrahydrofolate reductase 1

1

1

High-throughput

0.457

High

701905

SEH1
Nucleoporin SEH1

1

9

High-throughput

0.457

High

701911

ORM1
Protein ORM1

1

5

High-throughput

0.457

High

701918

ESBP6
Uncharacterized transporter ESBP6

1

5

High-throughput

0.457

High

701923

YMD7
Uncharacterized protein YML037C

1

1

High-throughput

0.457

High

701927

IVY1
Protein IVY1

1

1

High-throughput

0.457

High

701931

ORM2
Protein ORM2

1

5

High-throughput

0.457

High

701938

IMH1
Golgin IMH1

1

20

High-throughput

0.457

High

701942

TPO1
Polyamine transporter 1

1

1

High-throughput

0.457

High

701949

SSF2
Ribosome biogenesis protein SSF2

1

1

High-throughput

0.457

High

520953

G6PI
Glucose-6-phosphate isomerase

1

2

High-throughput

0.457

High

701865

SSZ1
Ribosome-associated complex subunit SSZ1

1

18

High-throughput

0.445

High

701919

APP1
Phosphatidate phosphatase APP1

2

0

High-throughput

0.307

High

692261

PT309
Pentatricopeptide repeat-containing protein PET309, mitochondrial

1

0

High-throughput

0.279

Low

701846

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.279

Low

434701

CHS1
Chitin synthase 1

1

0

High-throughput

0.261

Low

701847

MFA2
Mating hormone A-factor 2

1

0

High-throughput

0.261

Low

701852

SFK1
Protein SFK1

1

0

High-throughput

0.261

Low

701858

MRX3
MIOREX complex component 3

1

0

High-throughput

0.261

Low

701877

HPH2
Protein HPH2

1

0

High-throughput

0.261

Low

701886

PUP1
PUP1 protein homolog

1

0

High-throughput

0.261

Low

701891

PTR3
SPS-sensor component PTR3

1

0

High-throughput

0.261

Low

701900

YG3O
Uncharacterized protein YGR153W

1

0

High-throughput

0.261

Low

701908

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

1

0

High-throughput

0.261

Low

701913

SUN4
Probable secreted beta-glucosidase SUN4

1

0

High-throughput

0.261

Low

701936

OMS1
Methyltransferase OMS1, mitochondrial

1

0

High-throughput

0.261

Low

701943

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.261

Low

701948

YL125
Putative uncharacterized protein YLR125W

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024