HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 247
+	Hs
		817874 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		817898 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		683899 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		909937 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		881790 SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		905016 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		904490 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		982408 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		981953 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Sp
		737069 STE11_SCHPO (27-288): 1.28e-30: 122: 16.41		RAD24_SCHPO (3-247): 8.91e-135: 381: 60.82
+	Hs
		683645 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927430 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647206 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33