HitPredict

Interactor 1: RAC2 (P48554)
Ras-related protein Rac2
Gene: RAC2

Interactor 2: Q9VEV1 (Q9VEV1)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Pak3

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15777717
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PBD~Ras, Pkinase~Ras
Common GO terms	GO:0007520 - myoblast fusion GO:0050770 - regulation of axonogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 569
+	Dm
		776912 RAC1_DROME (1-192): 2.59e-81: 241: 93.23		Q9VEV1_DROME (1-569): 0: 544: 100.00
+	Hs
		564505 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		PAK1_HUMAN (8-568): 1.12e-157: 463: 37.48
+	Hs
		925244 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PAK1_HUMAN (8-568): 1.12e-157: 463: 37.48
+	Mm
		103566 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		G5E884_MOUSE (8-568): 3.18e-157: 462: 38.37
+	Mm
		292040 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		PAK1_MOUSE (8-568): 2.52e-155: 457: 36.95
+	Hs
		277602 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PAK3_HUMAN (8-568): 5.66e-152: 449: 35.94
+	Hs
		330841 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		PAK4_HUMAN (12-559): 3.86e-150: 445: 28.50
+	Hs
		330967 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PAK4_HUMAN (12-559): 3.86e-150: 445: 28.50
+	Dm
		776915 RAC1_DROME (1-192): 2.59e-81: 241: 93.23		PAK_DROME (9-568): 4.82e-151: 452: 34.33
+	Ce
		975572 RAC1_CAEEL (1-192): 1.93e-82: 244: 79.69		PK1_CAEEL (7-567): 6.87e-148: 439: 36.49
+	Hs
		564425 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		AKT2_HUMAN (157-568): 2.47e-133: 398: 21.70
+	Hs
		925648 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PAK6_HUMAN (98-563): 1.13e-129: 396: 33.69
+	Hs
		681775 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		AKT1_HUMAN (157-568): 4.36e-129: 388: 20.47
+	Dd
		332055 RACF1_DICDI (1-179): 1.03e-94: 275: 71.51		PAKB_DICDI (275-563): 7.43e-75: 256: 45.24
+	Dd
		710119 RACA_DICDI (1-186): 7.76e-81: 253: 62.90		PAKB_DICDI (275-563): 7.43e-75: 256: 45.24
+	Hs
		925763 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		M4K5_HUMAN (288-554): 9.28e-50: 186: 39.78
+	Hs
		925692 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PAK5_HUMAN (12-293): 1.07e-24: 110: 13.12
+	Hs
		564507 RHOQ_HUMAN (4-179): 1.12e-84: 250: 66.48		PAK2_HUMAN (17-156): 4.52e-22: 101: 20.57
+	Mm
		925809 RAC1_MOUSE (1-192): 5.39e-84: 248: 89.58		PAK2_MOUSE (17-189): 1.62e-22: 103: 19.43
+	Hs
		925245 RAC1_HUMAN (1-192): 5.39e-84: 248: 89.58		PAK2_HUMAN (17-156): 4.52e-22: 101: 20.57