Protein: CYSD
Homocysteine/cysteine synthase (EC 2.5.1.47) (EC 2.5.1.49) (O-acetylserine/O-acetylhomoserine sulfhydrylase) (OAS-OAH SHLase) (OAS-OAH sulfhydrylase)

Gene: CYSD, MET17
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P06106

Gene Ontology (top 5):
GO:0000103 - sulfate assimilation
GO:0003961 - O-acetylhomoserine aminocarboxypropyltransferase activity
GO:0004124 - cysteine synthase activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

391985

HSP82
ATP-dependent molecular chaperone HSP82

4

4

High-throughput

0.676

High

438789

CYSD
Homocysteine/cysteine synthase

1

13

Small-scale

0.575

High

438798

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.571

High

364226

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.501

High

438818

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.480

High

149480

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

434681

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

438796

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

438800

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

438802

KCC2
Calcium/calmodulin-dependent protein kinase II

1

3

High-throughput

0.479

High

438805

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

438811

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

438812

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

438814

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

438822

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

438803

SIS1
Protein SIS1

1

4

High-throughput

0.470

High

438791

F16P
Fructose-1,6-bisphosphatase

1

0

Small-scale

0.458

High

438799

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

438804

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

438808

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

438809

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

438815

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

438824

ESP1
Separin

1

0

High-throughput

0.458

High

438828

SGO1
Shugoshin

1

0

High-throughput

0.458

High

438830

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

438813

RCK1
Serine/threonine-protein kinase RCK1

1

3

High-throughput

0.457

High

438832

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

2

High-throughput

0.457

High

438823

IMA1
Importin subunit alpha

1

3

High-throughput

0.457

High

438797

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

383410

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

401808

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.437

High

409833

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433337

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

438790

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

438792

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

438806

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

438810

IXR1
Intrastrand cross-link recognition protein

1

1

Small-scale

0.437

High

438817

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

438820

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

438827

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

438829

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

438821

PTA1
Pre-tRNA-processing protein PTA1

1

0

High-throughput

0.269

Low

438825

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.269

Low

438801

DBF2
Cell cycle protein kinase DBF2

1

0

High-throughput

0.261

Low

438793

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

438794

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

438795

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

438807

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

438816

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

438819

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

438826

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

438831

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025