HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2157 Hs			1 126
+	Hs
		820873 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		821000 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		241475 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		821001 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		1127616 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		918418 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241550 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		918533 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707690 KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		807749 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		617932 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1O_HUMAN (1-126): 3.25e-54: 167: 99.21
+	Hs
		420812 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		807677 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		807743 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		807795 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		241473 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		707546 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		807658 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		807816 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B1N_HUMAN (1-126): 3.35e-53: 164: 98.41
+	Hs
		807775 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03