HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: LY9 (Q9HBG7)
T-lymphocyte surface antigen Ly-9 (Cell surface molecule Ly-9) (Lymphocyte antigen 9) (SLAM family member 3) (SLAMF3) (Signaling lymphocytic activation molecule 3) (CD antigen CD229)
Gene: LY9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15879090
Identification Methods	unspecified method, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 655
+	Hs
		557632 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DCC_HUMAN (27-600): 7.25e-74: 261: 16.00
+	Hs
		297885 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		NFASC_HUMAN (210-611): 4.22e-24: 110: 9.89
+	Hs
		924478 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		PGBM_HUMAN (6-329): 5.34e-22: 103: 13.77
+	Hs
		411818 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		SLAF6_HUMAN (32-254): 9.4e-51: 180: 32.47
+	Mm
		722901 GRB2_MOUSE (1-217): 2.48e-76: 230: 99.54		CD22_MOUSE (61-431): 4.56e-15: 81.1: 17.40
+	Hs
		924845 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		CD244_HUMAN (44-379): 3.34e-14: 76.5: 17.31
+	Hs
		590607 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		CD22_HUMAN (253-637): 5.7e-13: 74.3: 12.07
+	Hs
		789096 ABL2_HUMAN (4-139): 9.61e-22: 94.7: 34.04		SLAF5_HUMAN (33-244): 1.73e-60: 207: 38.01
+	Hs
		411547 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		CD2_HUMAN (247-582): 7.92e-38: 145: 20.17
+	Mm
		763408 FYN_MOUSE (161-215): 4.44e-14: 72.3: 31.58		SLAF1_MOUSE (28-274): 2.46e-46: 169: 23.31
+	Hs
		412176 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		SLAF1_HUMAN (25-263): 4.62e-43: 160: 24.41
+	Hs
		411561 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		CD48_HUMAN (60-243): 2.02e-18: 86.9: 19.57
+	Hs
		411939 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		CD2_HUMAN (247-582): 7.92e-38: 145: 20.17
+	Hs
		297883 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		NFASC_HUMAN (210-611): 4.22e-24: 110: 9.89
+	Hs
		297880 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		NFASC_HUMAN (210-611): 4.22e-24: 110: 9.89
+	Hs
		297881 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		NFASC_HUMAN (210-611): 4.22e-24: 110: 9.89
+	Hs
		782823 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		CD244_HUMAN (44-379): 3.34e-14: 76.5: 17.31
+	Hs
		433507 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		TUTLB_HUMAN (24-471): 5.62e-20: 97: 12.14
+	Hs
		234472 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		DSCAM_HUMAN (18-383): 4.98e-10: 65.1: 11.11
+	Hs
		412347 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		CD244_HUMAN (44-379): 3.34e-14: 76.5: 17.31