HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	27705803, 33022573, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 334
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (1-334): 2.77e-131: 379: 100.00
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		821390 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (2-289): 1.55e-94: 288: 29.49
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (5-251): 5.05e-84: 263: 27.89
+	Hs
		826854 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR83_HUMAN (25-333): 8.76e-84: 257: 31.83
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		1202777 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5B_HUMAN (3-198): 4.87e-59: 194: 30.10
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (197-332): 1.05e-32: 128: 22.54
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (248-333): 6.9e-13: 70.4: 25.29
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (198-333): 4.06e-28: 116: 30.15
+	Cr
		65492 A8J7J2_CHLRE (6-540): 0: 588: 66.17		MUT11_CHLRE (246-333): 2.1e-18: 86.6: 28.41
+	Cr
		65475 A8II42_CHLRE (15-534): 0: 577: 34.10		MUT11_CHLRE (246-333): 2.1e-18: 86.6: 28.41
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		1240450 TCPH_HUMAN (12-539): 0: 570: 29.64		POC1A_HUMAN (10-75): 1.3e-13: 73.1: 22.73
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39
+	Hs
		197078 TCPH_HUMAN (12-539): 0: 570: 29.64		PRP4_HUMAN (244-333): 1.12e-10: 64.2: 19.39