HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: FAN (Q92636)
Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation)
Gene: NSMAF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 917
+	Hs
		826801 TCPG_HUMAN (14-540): 0: 572: 33.15		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		1268696 TCPH_HUMAN (12-539): 0: 570: 29.64		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (743-915): 1.38e-54: 194: 19.89
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (525-778): 4.39e-45: 171: 13.97
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (751-916): 3.12e-44: 167: 14.22
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (445-739): 3.34e-63: 218: 13.96
+	Hs
		1202777 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5B_HUMAN (445-739): 3.34e-63: 218: 13.96
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (743-915): 1.38e-54: 194: 19.89
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (743-915): 1.38e-54: 194: 19.89
+	Hs
		573346 TCPA_HUMAN (26-541): 0: 545: 32.08		WDR5B_HUMAN (445-739): 3.34e-63: 218: 13.96
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (525-786): 1.85e-46: 180: 17.36
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (525-778): 4.39e-45: 171: 13.97
+	Hs
		573201 TCPA_HUMAN (26-541): 0: 545: 32.08		WDR5_HUMAN (743-915): 1.38e-54: 194: 19.89
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (751-916): 3.12e-44: 167: 14.22
+	Hs
		1240450 TCPH_HUMAN (12-539): 0: 570: 29.64		POC1A_HUMAN (751-916): 3.12e-44: 167: 14.22
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (454-574): 1.09e-09: 63.9: 9.52
+	Cr
		65492 A8J7J2_CHLRE (6-540): 0: 588: 66.17		MUT11_CHLRE (762-916): 3.46e-11: 68.2: 26.42
+	Cr
		65475 A8II42_CHLRE (15-534): 0: 577: 34.10		MUT11_CHLRE (762-916): 3.46e-11: 68.2: 26.42
+	Mm
		93126 TCPG_MOUSE (14-540): 0: 574: 33.33		E9PV60_MOUSE (836-917): 1.06e-09: 65: 20.21
+	Hs
		1306704 TCPH_HUMAN (12-539): 0: 570: 29.64		NLE1_HUMAN (454-574): 1.09e-09: 63.9: 9.52