Interactor 1: PK3CG (P48736)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)
Gene: PIK3CG

Interactor 2: PI3R6 (Q5UE93)
Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3-kinase gamma adapter protein of 87 kDa) (p84 PI3K adapter protein) (p84 PIKAP) (p87 PI3K adapter protein) (p87PIKAP)
Gene: PIK3R6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 16476736
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PI3K_1B_p101~PI3K_C2
Common GO terms GO:0001525 - angiogenesis
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005943 - phosphatidylinositol 3-kinase complex, class IA
GO:0005944 - phosphatidylinositol 3-kinase complex, class IB
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1102
Hs

1 754
+ Mm
+ Hs
+ Mm
+ Ss

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024