Protein: YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1 (EC 3.4.24.-) (Protein OSD1) (Tat-binding homolog 11) (Yeast mitochondrial escape protein 1)

Gene: YME1
Organism: Saccharomyces cerevisiae S288C
Interactions: 50
UniProt ID: P32795

Gene Ontology (top 5):
GO:0004176 - ATP-dependent peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

677065

MGR1
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1

3

1

Small-scale

0.667

High

745123

MIC60
MICOS complex subunit MIC60

3

3

High-throughput

0.640

High

679512

CDC48
Cell division control protein 48

1

10

High-throughput

0.618

High

745119

HSP78
Heat shock protein 78, mitochondrial

1

8

High-throughput

0.618

High

745127

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

15

Small-scale

0.618

High

745117

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

2

3

Small-scale

0.584

High

745135

TOM22
Mitochondrial import receptor subunit TOM22

2

2

High-throughput

0.584

High

745141

MGR3
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3

2

1

Small-scale

0.584

High

661775

TOM40
Mitochondrial import receptor subunit TOM40

2

3

High-throughput

0.571

High

745116

TIM12
Mitochondrial import inner membrane translocase subunit TIM12

1

1

Small-scale

0.501

High

745118

SWE1
Mitosis inhibitor protein kinase SWE1

1

12

High-throughput

0.501

High

745136

TIM13
Mitochondrial import inner membrane translocase subunit TIM13

1

1

Small-scale

0.501

High

745138

TIM10
Mitochondrial import inner membrane translocase subunit TIM10

1

1

Small-scale

0.501

High

267939

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

1

0

Small-scale

0.480

High

382861

RMAR
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.479

High

510325

HSP77
Import motor subunit, mitochondrial

1

10

High-throughput

0.479

High

523431

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.479

High

579081

HSC82
ATP-dependent molecular chaperone HSC82

1

12

High-throughput

0.479

High

638894

CBP3
Protein CBP3, mitochondrial

1

1

High-throughput

0.479

High

736221

RM41
Large ribosomal subunit protein uL23m

1

1

High-throughput

0.479

High

745126

XDJ1
DnaJ protein homolog XDJ1

1

7

High-throughput

0.479

High

745128

OXA1
Mitochondrial inner membrane protein OXA1

1

3

High-throughput

0.479

High

745129

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

1

High-throughput

0.479

High

745130

MPM1
Mitochondrial peculiar membrane protein 1

1

1

High-throughput

0.479

High

745137

ATP23
Mitochondrial inner membrane protease ATP23

1

1

High-throughput

0.479

High

745145

YD157
Uncharacterized protein YDL157C, mitochondrial

1

1

Small-scale

0.479

High

745147

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

3

High-throughput

0.479

High

745121

UPS2
Protein UPS2, mitochondrial

1

0

Small-scale

0.458

High

745131

ATG32
Autophagy-related protein 32

1

0

Small-scale

0.458

High

745133

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

Small-scale

0.458

High

745142

TAZ
Tafazzin

1

0

Small-scale

0.458

High

745144

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

0

Small-scale

0.458

High

745139

UBC7
Ubiquitin-conjugating enzyme E2 7

1

5

High-throughput

0.457

High

526241

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

544254

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

574863

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.438

High

383596

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

502936

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

512903

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

674506

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.437

High

706590

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

745120

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

745122

CENPA
Histone H3-like centromeric protein CSE4

1

4

High-throughput

0.437

High

745124

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.437

High

745132

T2FA
Transcription initiation factor IIF subunit alpha

1

1

High-throughput

0.437

High

745134

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

745140

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.437

High

745143

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.437

High

745125

ATG12
Ubiquitin-like protein ATG12

1

2

High-throughput

0.417

High

745146

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025