HitPredict

Interactor 1: BNR1 (P40450)
BNI1-related protein 1
Gene: BNR1

Interactor 2: CYK2 (Q05080)
Cytokinesis protein 2 (Homolog of CDC15 protein 1)
Gene: HOF1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

Property	Details
Experiments	9774458, 11743162, 30076201, 19841731
Identification Methods	affinity chromatography technology, two hybrid, pull down, two hybrid array, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005935 - cellular bud neck GO:0032153 - cell division site GO:0051015 - actin filament binding GO:0051017 - actin filament bundle assembly GO:1903475 - mitotic actomyosin contractile ring assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1375 Sc			1 669
+	Sc
		805398 BNR1_YEAST (1-1375): 0: 1129: 100.00		BZZ1_YEAST (11-663): 2.23e-53: 195: 13.24
+	Hs
		258362 FMNL1_HUMAN (353-1365): 5.43e-151: 488: 15.48		GAS7_HUMAN (3-276): 4.16e-67: 229: 21.63
+	Sp
		1068586 CDC12_SCHPO (92-1375): 0: 594: 21.01		CDC15_SCHPO (275-665): 2.24e-27: 120: 14.92
+	Hs
		252392 DIAP1_HUMAN (345-1372): 4.95e-140: 462: 17.71		GAS7_HUMAN (3-276): 4.16e-67: 229: 21.63
+	Sc
		836335 BNI1_YEAST (187-727): 1.49e-62: 237: 14.58		CYK2_YEAST (1-669): 1.91e-104: 333: 100.00
+	Dm
		118386 DIA_DROME (827-1327): 7.81e-94: 330: 17.45		M9NE16_DROME (1-664): 1.22e-53: 196: 11.92
+	Sc
		798416 BNI1_YEAST (187-727): 1.49e-62: 237: 14.58		RGD1_YEAST (12-445): 6.54e-73: 250: 16.85
+	Sc
		805404 BNI1_YEAST (187-727): 1.49e-62: 237: 14.58		BZZ1_YEAST (11-663): 2.23e-53: 195: 13.24
+	Hs
		1211659 DAAM1_HUMAN (92-600): 4.55e-09: 63.5: 12.57		FBP1L_HUMAN (1-664): 1.66e-66: 231: 14.58
+	Hs
		1402037 DAAM1_HUMAN (92-600): 4.55e-09: 63.5: 12.57		FNBP1_HUMAN (1-664): 7.19e-64: 224: 13.33
+	Hs
		1150902 DAAM1_HUMAN (92-600): 4.55e-09: 63.5: 12.57		CIP4_HUMAN (1-664): 3.39e-52: 192: 11.89