Interactor 1: MK08 (P49185)
Mitogen-activated protein kinase 8 (MAP kinase 8) (MAPK 8) (EC 2.7.11.24) (SAPK gamma) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (p54 gamma)
Gene: Mapk8

Interactor 2: Q4KSH6 (Q4KSH6)
mitogen-activated protein kinase kinase (EC 2.7.12.2)
Gene: Map2k4

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17568772
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0007254 - JNK cascade
GO:0030424 - axon
GO:0032839 - dendrite cytoplasm
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 411
Rn

1 397
+ Hs
+ Mm
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+ Mm
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+ Dm
+ At
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+ Ce
+ At
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024