Interactor 1: FAS (P49327)
Fatty acid synthase (EC 2.3.1.85) (Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]
Gene: FASN
Interactor 2: FAS (P49327)
Fatty acid synthase (EC 2.3.1.85) (Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.39); Acyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)]
Gene: FASN
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.621 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11248039 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Acyl_transf_1~Acyl_transf_1, Acyl_transf_1~KAsynt_C_assoc, Acyl_transf_1~PP-binding, ADH_zinc_N~ADH_zinc_N, KAsynt_C_assoc~KAsynt_C_assoc, KAsynt_C_assoc~ketoacyl-synt, KAsynt_C_assoc~Ketoacyl-synt_C, ketoacyl-synt~ketoacyl-synt, Ketoacyl-synt_C~ketoacyl-synt, PP-binding~ketoacyl-synt, Ketoacyl-synt_C~Ketoacyl-synt_C, KR~KR, Methyltransf_12~Methyltransf_12, PP-binding~PP-binding, PP-binding~Thioesterase, Thioesterase~Thioesterase |
| Common GO terms | GO:0001649 - osteoblast differentiation GO:0002068 - glandular epithelial cell development GO:0003723 - RNA binding GO:0004312 - fatty acid synthase activity GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity and 29 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
