Interactor 1: CDK8 (P49336)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)
Gene: CDK8
Interactor 2: MED18 (Q9BUE0)
Mediator of RNA polymerase II transcription subunit 18 (Mediator complex subunit 18) (p28b)
Gene: MED18
Species: Homo sapiens
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.60 | 0.750 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 33961781, 26496610, 29568061, 24981860, 23602568, unassigned1655 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016592 - mediator complex GO:0016567 - protein ubiquitination and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
