Protein: INP53
Polyphosphatidylinositol phosphatase INP53 (Suppressor of PMA1 protein 2) (Synaptojanin-like protein 3) [Includes: SAC1-like phosphoinositide phosphatase (EC 3.1.3.-); Phosphatidylinositol 4,5-bisphosphate 5-phosphatase (EC 3.1.3.36)]

Gene: INP53
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: Q12271

Gene Ontology (top 5):
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005737 - cytoplasm
GO:0006897 - endocytosis
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

644858

CLH
Clathrin heavy chain

4

4

Small-scale

0.684

High

1055892

BSP1
F-actin capping regulator BSP1

2

1

Small-scale

0.620

High

744944

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

4

Small-scale

0.614

High

805451

BZZ1
Protein BZZ1

2

11

Small-scale

0.614

High

745061

YSC84
Protein YSC84

1

20

High-throughput

0.541

High

850508

LSB3
LAS seventeen-binding protein 3

1

20

High-throughput

0.541

High

722363

XPO1
Exportin-1

1

6

High-throughput

0.536

High

798433

RGD1
RHO GTPase-activating protein RGD1

1

2

High-throughput

0.536

High

1043608

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.513

High

778873

AP1B1
AP-1 complex subunit beta-1

1

11

High-throughput

0.494

High

805317

GGA2
ADP-ribosylation factor-binding protein GGA2

1

2

High-throughput

0.494

High

1084141

AP1G1
AP-1 complex subunit gamma-1

1

14

High-throughput

0.494

High

864143

LSM1
LSM1-LSM7 complex subunit LSM1

1

0

High-throughput

0.486

High

575623

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

3

Small-scale

0.479

High

762933

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.479

High

812771

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

814308

RV167
Reduced viability upon starvation protein 167

1

20

Small-scale

0.479

High

585521

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

795599

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

866297

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

546766

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

676470

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

742691

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

820133

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

671249

SIS1
Protein SIS1

1

6

High-throughput

0.437

High

708546

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

826940

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.437

High

850266

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.437

High

1065540

AP3D
AP-3 complex subunit delta

1

14

High-throughput

0.437

High

824589

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

912469

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

1044210

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.265

Low

361023

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

584330

DPOD
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.249

Low

594640

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

793640

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025