Protein: INP52
Polyphosphatidylinositol phosphatase INP52 (Synaptojanin-like protein 2) [Includes: SAC1-like phosphoinositide phosphatase (EC 3.1.3.-); Phosphatidylinositol 4,5-bisphosphate 5-phosphatase (EC 3.1.3.36)]

Gene: INP52
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P50942

Gene Ontology (top 5):
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004439 - phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005737 - cytoplasm
GO:0006897 - endocytosis
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

587323

ABP1
Actin-binding protein

5

11

Small-scale

0.720

High

744888

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

4

4

Small-scale

0.697

High

898917

BSP1
F-actin capping regulator BSP1

1

1

Small-scale

0.573

High

798154

ARPC1
Actin-related protein 2/3 complex subunit 1

1

2

High-throughput

0.541

High

850445

LSB3
LAS seventeen-binding protein 3

1

20

High-throughput

0.541

High

518335

IF4A
ATP-dependent RNA helicase eIF4A

1

2

High-throughput

0.536

High

545542

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.536

High

813296

FHP
Flavohemoprotein

1

1

High-throughput

0.536

High

554715

YPK1
Serine/threonine-protein kinase YPK1

1

1

High-throughput

0.515

High

644814

CLH
Clathrin heavy chain

1

4

Small-scale

0.515

High

671968

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

1

High-throughput

0.515

High

417145

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.513

High

866013

ADK
Adenosine kinase

1

0

High-throughput

0.513

High

656333

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

3

Small-scale

0.501

High

679868

CDC48
Cell division control protein 48

1

1

High-throughput

0.500

High

865002

TCPQ
T-complex protein 1 subunit theta

1

1

High-throughput

0.500

High

898910

ACT
Actin

1

8

High-throughput

0.500

High

524542

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.479

High

592364

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.479

High

656984

BUR1
Serine/threonine-protein kinase BUR1

1

3

High-throughput

0.470

High

800665

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.458

High

865384

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

1

0

High-throughput

0.458

High

898909

VPS4
Vacuolar protein sorting-associated protein 4

1

2

High-throughput

0.457

High

898916

MLC2
Myosin light chain 2

1

4

High-throughput

0.457

High

405113

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

626812

HSP60
Heat shock protein 60, mitochondrial

1

3

High-throughput

0.457

High

393027

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.445

High

510651

HSP77
Import motor subunit, mitochondrial

1

10

High-throughput

0.445

High

676161

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

819250

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.445

High

668435

PTP1
Tyrosine-protein phosphatase 1

1

0

High-throughput

0.438

High

817786

RT105
Regulator of Ty1 transposition protein 105

1

0

High-throughput

0.438

High

898912

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.438

High

538345

PYC1
Pyruvate carboxylase 1

1

1

High-throughput

0.437

High

603512

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.437

High

707629

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

826654

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.437

High

898913

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

898918

AP3D
AP-3 complex subunit delta

1

14

High-throughput

0.437

High

816725

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

898911

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

673114

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.279

Low

781718

SA190
SIT4-associating protein SAP190

1

0

High-throughput

0.279

Low

898915

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.279

Low

479989

PRTB
Cerevisin

1

0

High-throughput

0.269

Low

814143

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.269

Low

898914

DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.269

Low

835940

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025