HitPredict

Interactor 1: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17620599
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005159 - insulin-like growth factor receptor binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 247
+	Hs
		827146 ARRB1_HUMAN (1-418): 0: 716: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		827172 ARRB1_HUMAN (1-418): 0: 716: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		683201 ARRB1_HUMAN (1-418): 0: 716: 100.00		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		827158 ARRB1_HUMAN (1-418): 0: 716: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		685876 ARRB2_HUMAN (1-407): 0: 626: 76.15		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		646723 ARRB1_HUMAN (1-418): 0: 716: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		685872 ARRB2_HUMAN (1-407): 0: 626: 76.15		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		685919 ARRB2_HUMAN (1-407): 0: 626: 76.15		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		683162 ARRB2_HUMAN (1-407): 0: 626: 76.15		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		646667 ARRB2_HUMAN (1-407): 0: 626: 76.15		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33