HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	34079125, 20080577, 19410545
Identification Methods	proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 425
+	Hs
		934696 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Mm
		935452 H31_MOUSE (5-134): 1.29e-52: 164: 48.86		RBBP4_MOUSE (1-425): 4.3e-124: 367: 100.00
+	Hs
		997742 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00
+	Mm
		952258 H32_MOUSE (5-134): 1.73e-51: 161: 48.86		RBBP4_MOUSE (1-425): 4.3e-124: 367: 100.00
+	Hs
		828241 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		934809 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		1083261 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		1083292 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Mm
		935449 H31_MOUSE (5-134): 1.29e-52: 164: 48.86		Q3UJI2_MOUSE (1-425): 6.93e-114: 341: 88.97
+	Mm
		952255 H32_MOUSE (5-134): 1.73e-51: 161: 48.86		Q3UJI2_MOUSE (1-425): 6.93e-114: 341: 88.97
+	Mm
		952742 H33_MOUSE (5-134): 1.57e-51: 161: 49.62		Q3UJI2_MOUSE (1-425): 6.93e-114: 341: 88.97
+	Hs
		267767 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		TAF5L_HUMAN (26-422): 3e-74: 244: 22.20
+	Hs
		935208 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52
+	Hs
		934796 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23
+	Hs
		1074789 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23
+	Hs
		245614 H32_HUMAN (5-134): 1.73e-51: 161: 48.86		TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63
+	Hs
		903117 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		903260 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		935175 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56
+	Hs
		934971 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		DAW1_HUMAN (9-106): 2.42e-20: 94.1: 8.74