HitPredict

Interactor 1: NUP42 (P49686)
Nucleoporin NUP42 (Nuclear pore protein NUP42)
Gene: NUP42

Interactor 2: IMB1 (Q06142)
Importin subunit beta-1 (Importin-95) (Karyopherin subunit beta-1) (Karyopherin-95)
Gene: KAP95

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.727

Property	Details
Experiments	11387327, 12917401, 9368759, 17897934, 22357553, 17418788
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 430 Sc			1 861
+	Sc
		830681 NU145_YEAST (35-416): 3.3e-37: 146: 16.75		IMB1_YEAST (1-861): 3.78e-177: 534: 100.00
+	Hs
		727254 NU214_HUMAN (2-398): 4.04e-35: 140: 19.51		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Sc
		774378 NU159_YEAST (4-382): 6.37e-20: 94.9: 25.07		IMB1_YEAST (1-861): 3.78e-177: 534: 100.00
+	Sc
		541927 NSP1_YEAST (2-421): 1.81e-13: 74.5: 12.47		IMB1_YEAST (1-861): 3.78e-177: 534: 100.00
+	Sc
		687968 NUP42_YEAST (1-430): 1.55e-62: 210: 100.00		IMB3_YEAST (7-813): 1.96e-115: 379: 16.43
+	Hs
		857978 NUP98_HUMAN (46-360): 1.85e-13: 74.9: 14.03		IMB1_HUMAN (4-857): 7.07e-167: 509: 32.96
+	Xl
		853820 Q6DCP4_XENLA (25-414): 2.12e-10: 64.5: 17.59		IMB_XENLA (4-857): 2.14e-165: 505: 32.96
+	Hs
		727300 NU214_HUMAN (2-398): 4.04e-35: 140: 19.51		TNPO1_HUMAN (12-807): 1.04e-126: 404: 15.37
+	Sc
		687969 NU145_YEAST (35-416): 3.3e-37: 146: 16.75		IMB3_YEAST (7-813): 1.96e-115: 379: 16.43
+	Hs
		858024 NUP98_HUMAN (46-360): 1.85e-13: 74.9: 14.03		TNPO1_HUMAN (12-807): 1.04e-126: 404: 15.37
+	Sc
		687954 NU159_YEAST (4-382): 6.37e-20: 94.9: 25.07		IMB3_YEAST (7-813): 1.96e-115: 379: 16.43
+	Hs
		155553 NUP98_HUMAN (46-360): 1.85e-13: 74.9: 14.03		TNPO2_HUMAN (15-807): 3.1e-120: 387: 15.44
+	Xl
		1137359 NU153_XENLA (14-421): 2.25e-09: 61.8: 14.56		Q5U4V0_XENLA (12-807): 3.64e-124: 397: 14.94
+	Sc
		541851 NSP1_YEAST (2-421): 1.81e-13: 74.5: 12.47		IMB3_YEAST (7-813): 1.96e-115: 379: 16.43
+	Ce
		248176 Q21295_CAEEL (72-270): 2.72e-16: 82.9: 21.05		O62332_CAEEL (2-823): 2.89e-99: 331: 16.17
+	Ce
		248185 Q9U3B9_CAEEL (1-270): 8.22e-15: 78.4: 20.36		O62332_CAEEL (2-823): 2.89e-99: 331: 16.17
+	Sc
		767684 NUP42_YEAST (1-430): 1.55e-62: 210: 100.00		IMB4_YEAST (5-756): 1.06e-49: 192: 14.36
+	Sc
		767656 NU159_YEAST (4-382): 6.37e-20: 94.9: 25.07		IMB4_YEAST (5-756): 1.06e-49: 192: 14.36
+	Sc
		541885 NSP1_YEAST (2-421): 1.81e-13: 74.5: 12.47		IMB4_YEAST (5-756): 1.06e-49: 192: 14.36
+	Hs
		127197 NU214_HUMAN (2-398): 4.04e-35: 140: 19.51		IPO5_HUMAN (4-604): 5.13e-11: 68.8: 9.23