HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 2725
+	Hs
		708641 MCM5_HUMAN (169-902): 0: 768: 29.43		FLNC_HUMAN (1-2725): 0: 2507: 100.00
+	Hs
		598011 MCM2_HUMAN (1-904): 0: 1078: 100.00		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261224 MCM2_HUMAN (1-904): 0: 1078: 100.00		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		597978 MCM5_HUMAN (169-902): 0: 768: 29.43		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261208 MCM5_HUMAN (169-902): 0: 768: 29.43		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		521499 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		211532 MCM2_HUMAN (1-904): 0: 1078: 100.00		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		832590 MCM2_HUMAN (1-904): 0: 1078: 100.00		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		832656 MCM2_HUMAN (1-904): 0: 1078: 100.00		HMCN1_HUMAN (786-2707): 3.41e-96: 352: 11.24
+	Hs
		832370 MCM2_HUMAN (1-904): 0: 1078: 100.00		PGBM_HUMAN (1306-2725): 4.84e-73: 276: 11.87
+	Hs
		362945 MCM2_HUMAN (1-904): 0: 1078: 100.00		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		521479 MCM5_HUMAN (169-902): 0: 768: 29.43		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		832607 MCM2_HUMAN (1-904): 0: 1078: 100.00		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Hs
		362873 MCM5_HUMAN (169-902): 0: 768: 29.43		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		362828 MCM3_HUMAN (186-897): 0: 725: 29.20		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		363148 MCM6_HUMAN (186-817): 0: 710: 31.18		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		362874 MCM7_HUMAN (188-886): 0: 707: 27.35		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83