Interactor 1: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1

Interactor 2: APBA1 (Q02410)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.629

The method score is based on:

Property Details
Experiments 11083918, 16007100
Identification Methods anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0008021 - synaptic vesicle
GO:0010468 - regulation of gene expression
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 467
Hs

1 837
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024