Protein: NEMO
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)

Gene: NEMO, Ikbkg
Organism: Mus musculus
Interactions: 58
UniProt ID: O88522

Gene Ontology (top 5):
GO:0001782 - B cell homeostasis
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
GO:0007249 - canonical NF-kappaB signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

291432

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

18

17

Small-scale

0.984

High

291800

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

11

20

Small-scale

0.970

High

291826

IKBA
NF-kappa-B inhibitor alpha

5

20

Small-scale

0.917

High

291773

NEMO
NF-kappa-B essential modulator

4

17

Small-scale

0.874

High

291802

IKBB
NF-kappa-B inhibitor beta

2

20

Small-scale

0.778

High

291815

RNF31
E3 ubiquitin-protein ligase RNF31

4

16

Small-scale

0.705

High

291818

IKBZ
NF-kappa-B inhibitor zeta

1

14

High-throughput

0.698

High

291787

TRAF6
TNF receptor-associated factor 6

4

19

Small-scale

0.680

High

291801

TNAP3
Tumor necrosis factor alpha-induced protein 3

3

12

Small-scale

0.680

High

291779

TNR1A
Tumor necrosis factor receptor superfamily member 1A

4

7

Small-scale

0.676

High

291788

TANK
TRAF family member-associated NF-kappa-B activator

3

1

Small-scale

0.640

High

291803

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

3

20

Small-scale

0.640

High

291778

HS71B
Heat shock 70 kDa protein 1B

2

10

Small-scale

0.601

High

291805

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

5

Small-scale

0.601

High

291774

TNFA
Tumor necrosis factor

2

3

Small-scale

0.584

High

291781

AKT1
RAC-alpha serine/threonine-protein kinase

2

13

Small-scale

0.584

High

291782

TRAF2
TNF receptor-associated factor 2

2

14

Small-scale

0.584

High

291808

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

2

3

Small-scale

0.584

High

291823

TBK1
Serine/threonine-protein kinase TBK1

2

20

Small-scale

0.584

High

291775

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

13

High-throughput

0.579

High

291822

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

11

Small-scale

0.561

High

291777

TFE2
Transcription factor E2-alpha

1

2

High-throughput

0.541

High

291795

NFE2
Transcription factor NF-E2 45 kDa subunit

1

2

High-throughput

0.541

High

291804

TS101
Tumor susceptibility gene 101 protein

1

2

High-throughput

0.541

High

291807

MAML1
Mastermind-like protein 1

1

9

High-throughput

0.541

High

291780

TNR5
Tumor necrosis factor receptor superfamily member 5

1

7

Small-scale

0.515

High

291820

TLR4
Toll-like receptor 4

1

3

Small-scale

0.515

High

291814

SHRPN
Sharpin

1

3

Small-scale

0.500

High

60472

A5D6Q2
Ncoa3 protein

1

11

High-throughput

0.481

High

291776

ANXA1
Annexin A1

1

4

Small-scale

0.479

High

291785

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

8

Small-scale

0.479

High

291786

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

2

Small-scale

0.479

High

291789

IRF7
Interferon regulatory factor 7

1

2

Small-scale

0.479

High

291792

SMN
Survival motor neuron protein

1

2

Small-scale

0.479

High

291793

KPCT
Protein kinase C theta type

1

9

Small-scale

0.479

High

291797

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

291806

SENP6
Sentrin-specific protease 6

1

1

Small-scale

0.479

High

291811

TRI29
Tripartite motif-containing protein 29

1

15

Small-scale

0.479

High

291812

MAVS
Mitochondrial antiviral-signaling protein

1

8

Small-scale

0.479

High

291813

SOCS7
Suppressor of cytokine signaling 7

1

1

Small-scale

0.479

High

291817

GDIR1
Rho GDP-dissociation inhibitor 1

1

1

Small-scale

0.479

High

291819

RHOA
Transforming protein RhoA

1

20

Small-scale

0.479

High

291821

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

20

Small-scale

0.479

High

291824

GSK3B
Glycogen synthase kinase-3 beta

1

12

Small-scale

0.479

High

291825

BCL10
B-cell lymphoma/leukemia 10

1

1

Small-scale

0.479

High

291798

NLRX1
NLR family member X1

1

3

Small-scale

0.470

High

291791

NKX32
Homeobox protein Nkx-3.2

1

0

Small-scale

0.458

High

291796

PADI2
Protein-arginine deiminase type-2

1

0

Small-scale

0.458

High

291794

Q05BA5
Nuclear receptor coactivator

1

10

High-throughput

0.457

High

291783

TNR4
Tumor necrosis factor receptor superfamily member 4

1

7

Small-scale

0.457

High

291784

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

Small-scale

0.445

High

291799

ZC12A
Endoribonuclease ZC3H12A

1

2

Small-scale

0.445

High

291816

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

20

Small-scale

0.445

High

101503

F8VQ72
Mitogen-activated protein kinase kinase kinase 1

1

4

Small-scale

0.437

High

291790

BID
BH3-interacting domain death agonist

1

1

Small-scale

0.437

High

291810

ANGL8
Angiopoietin-like protein 8

1

1

Small-scale

0.437

High

291809

RHBD3
Rhomboid domain-containing protein 3

1

0

Small-scale

0.292

High


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Last updated: 15 Jul 2024