Interactor 1: EI2BB (P49770)
Translation initiation factor eIF2B subunit beta (S20I15) (S20III15) (eIF2B GDP-GTP exchange factor subunit beta)
Gene: EIF2B2

Interactor 2: EI2BA (Q14232)
Translation initiation factor eIF2B subunit alpha (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: EIF2B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 28514442, 27173435, 33961781, 21795329
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 351
Hs

1 305
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Sp
+ Ce
+ Sc
+ Hs
+ Sc
+ Sc
+ Hv
+ Sc

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Last updated: 15 Jul 2024