HitPredict

Interactor 1: RGS3 (P49796)
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Gene: RGS3

Interactor 2: SEPT2 (Q15019)
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)
Gene: SEPTIN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1198 Hs			1 361
+	Hs
		834917 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEPT8_HUMAN (3-348): 2.74e-162: 464: 39.54
+	Hs
		834928 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEP11_HUMAN (8-348): 3.99e-161: 459: 39.83
+	Hs
		834931 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEP10_HUMAN (14-357): 7.49e-159: 454: 38.00
+	Hs
		566499 KPCA_HUMAN (124-271): 6.07e-71: 253: 30.87		SEPT9_HUMAN (2-320): 2.97e-159: 460: 45.68
+	Hs
		566387 KPCA_HUMAN (124-271): 6.07e-71: 253: 30.87		SEPT6_HUMAN (14-348): 5.19e-160: 457: 40.24