HitPredict

Interactor 1: RGS2 (P49808)
Regulator of G-protein signaling rgs-2
Gene: rgs-2

Interactor 2: GNAO (P51875)
Guanine nucleotide-binding protein G(o) subunit alpha
Gene: goa-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	10950865
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 169 Ce			1 354
+	Hs
		283160 RGS20_HUMAN (15-166): 2.7e-65: 205: 57.24		GNAO_HUMAN (1-354): 2.13e-174: 490: 82.20
+	Hs
		391357 RGS3_HUMAN (13-165): 3.26e-62: 208: 35.29		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		283183 RGS20_HUMAN (15-166): 2.7e-65: 205: 57.24		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Hs
		283156 RGS20_HUMAN (15-166): 2.7e-65: 205: 57.24		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		444692 RGS3_HUMAN (13-165): 3.26e-62: 208: 35.29		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		277782 RGS9_HUMAN (16-168): 2.6e-57: 191: 32.68		GNAO_HUMAN (1-354): 2.13e-174: 490: 82.20
+	Hs
		450988 RGS19_HUMAN (13-168): 2.03e-61: 190: 53.21		GNAO_HUMAN (1-354): 2.13e-174: 490: 82.20
+	Hs
		926723 RGS17_HUMAN (8-167): 3.14e-62: 192: 51.25		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Hs
		834879 RGS19_HUMAN (13-168): 2.03e-61: 190: 53.21		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Hs
		207517 RGS14_HUMAN (2-164): 5.81e-57: 189: 29.59		GNAI1_HUMAN (1-354): 3.13e-172: 484: 69.86
+	Ce
		711280 RGS1_CAEEL (1-169): 1.92e-62: 192: 64.50		GNAO_CAEEL (1-354): 5.39e-171: 481: 100.00
+	Hs
		391356 RGS19_HUMAN (13-168): 2.03e-61: 190: 53.21		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		207505 RGS14_HUMAN (2-164): 5.81e-57: 189: 29.59		GNAI2_HUMAN (1-354): 1.57e-171: 482: 68.17
+	Hs
		444806 RGS17_HUMAN (8-167): 3.14e-62: 192: 51.25		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		444691 RGS19_HUMAN (13-168): 2.03e-61: 190: 53.21		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		207507 RGS14_HUMAN (2-164): 5.81e-57: 189: 29.59		GNAI3_HUMAN (1-354): 2.32e-169: 477: 69.86
+	Hs
		670435 RGS3_HUMAN (13-165): 3.26e-62: 208: 35.29		GNA11_HUMAN (1-353): 1.08e-158: 450: 48.02
+	Hs
		283162 RGS20_HUMAN (15-166): 2.7e-65: 205: 57.24		GNAZ_HUMAN (1-353): 1.44e-154: 440: 59.89
+	Hs
		207511 RGS14_HUMAN (2-164): 5.81e-57: 189: 29.59		GNA11_HUMAN (1-353): 1.08e-158: 450: 48.02
+	Hs
		580409 RGS19_HUMAN (13-168): 2.03e-61: 190: 53.21		GNAZ_HUMAN (1-353): 1.44e-154: 440: 59.89