Interactor 1: GRM5 (P41594)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5
Interactor 2: GRM5 (P41594)
Metabotropic glutamate receptor 5 (mGluR5)
Gene: GRM5
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.666 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30675062 |
| Identification Methods | 3D electron microscopy, x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_3~7tm_3, 7tm_3~NCD3G, ANF_receptor~ANF_receptor, ANF_receptor~NCD3G, NCD3G~NCD3G |
| Common GO terms | GO:0001640 - adenylate cyclase inhibiting G protein-coupled glutamate receptor activity GO:0002029 - desensitization of G protein-coupled receptor signaling pathway GO:0004930 - G protein-coupled receptor activity GO:0005737 - cytoplasm GO:0005886 - plasma membrane and 28 others more... |
| Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025