Protein: CASR
Extracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1)

Gene: CASR
Organism: Homo sapiens
Interactions: 23
UniProt ID: P41180

Gene Ontology (top 5):
GO:0001503 - ossification
GO:0002931 - response to ischemia
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0004930 - G protein-coupled receptor activity
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

832601

CASR
Extracellular calcium-sensing receptor

3

14

Small-scale

0.865

High

832605

GRM1
Metabotropic glutamate receptor 1

1

15

Small-scale

0.724

High

637381

FLNA
Filamin-A

2

3

Small-scale

0.642

High

296854

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

14

Small-scale

0.618

High

832612

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

14

Small-scale

0.618

High

832608

HIF1A
Hypoxia-inducible factor 1-alpha

2

0

Small-scale

0.598

High

832602

NOTC1
Neurogenic locus notch homolog protein 1

1

2

Small-scale

0.561

High

822498

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.537

High

340620

STABP
STAM-binding protein

1

0

Small-scale

0.529

High

683398

IKBA
NF-kappa-B inhibitor alpha

1

0

Small-scale

0.529

High

832609

HACE1
E3 ubiquitin-protein ligase HACE1

1

1

Small-scale

0.512

High

832607

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

Small-scale

0.506

High

424642

KPCG
Protein kinase C gamma type

1

8

Small-scale

0.501

High

436625

KPCB
Protein kinase C beta type

1

8

Small-scale

0.501

High

603192

KPCA
Protein kinase C alpha type

1

8

Small-scale

0.501

High

171193

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

2

Small-scale

0.479

High

832603

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

832604

NOTC2
Neurogenic locus notch homolog protein 2

1

2

Small-scale

0.479

High

832613

NOTC3
Neurogenic locus notch homolog protein 3

1

2

Small-scale

0.479

High

832610

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

1

Small-scale

0.437

High

832606

OS9
Protein OS-9

1

0

Small-scale

0.249

Low

832611

RN19A
E3 ubiquitin-protein ligase RNF19A

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025