Protein: GIT1
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)

Gene: GIT1
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q9Y2X7

Gene Ontology (top 5):
GO:0001957 - intramembranous ossification
GO:0005096 - GTPase activator activity
GO:0005739 - mitochondrion
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1049747

ARHG7
Rho guanine nucleotide exchange factor 7

13

20

Small-scale

0.982

High

823519

PAXI
Paxillin

9

12

Small-scale

0.968

High

1066061

ARHG6
Rho guanine nucleotide exchange factor 6

6

20

Small-scale

0.945

High

1026252

PAK1
Serine/threonine-protein kinase PAK 1

6

14

Small-scale

0.943

High

1026957

PAK2
Serine/threonine-protein kinase PAK 2

5

13

Small-scale

0.922

High

1050177

GIT2
ARF GTPase-activating protein GIT2

4

14

Small-scale

0.907

High

924974

GRB2
Growth factor receptor-bound protein 2

4

20

High-throughput

0.891

High

557838

NCK1
SH2/SH3 adapter protein NCK1

4

20

Small-scale

0.881

High

1377461

GIT1
ARF GTPase-activating protein GIT1

3

15

Small-scale

0.873

High

239000

LPXN
Leupaxin

3

16

Small-scale

0.866

High

209194

NCK2
Cytoplasmic protein NCK2

3

20

High-throughput

0.861

High

894610

CDC42
Cell division control protein 42 homolog

3

20

Small-scale

0.834

High

626670

ARBK1
Beta-adrenergic receptor kinase 1

3

9

Small-scale

0.827

High

925751

RAC1
Ras-related C3 botulinum toxin substrate 1

3

20

Small-scale

0.827

High

1349372

SPN90
NCK-interacting protein with SH3 domain

2

1

High-throughput

0.811

High

200193

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

2

15

Small-scale

0.806

High

1083229

KCC4
Calcium/calmodulin-dependent protein kinase type IV

3

10

High-throughput

0.779

High

907192

PRS8
26S proteasome regulatory subunit 8

2

0

High-throughput

0.770

High

581085

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

Small-scale

0.724

High

1305987

BARD1
BRCA1-associated RING domain protein 1

1

16

High-throughput

0.713

High

1301571

TRIB3
Tribbles homolog 3

1

9

High-throughput

0.698

High

1326383

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.698

High

587076

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.691

High

1377240

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

13

High-throughput

0.691

High

1025362

LIPA1
Liprin-alpha-1

3

9

Small-scale

0.684

High

1050094

SCRIB
Protein scribble homolog

4

13

Small-scale

0.678

High

1286567

ENTR1
Endosome-associated-trafficking regulator 1

3

2

Small-scale

0.674

High

863144

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

1

High-throughput

0.667

High

1357135

MAFF
Transcription factor MafF

3

1

High-throughput

0.667

High

983697

FAK1
Focal adhesion kinase 1

3

20

Small-scale

0.664

High

182228

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

6

High-throughput

0.656

High

851375

NEK2
Serine/threonine-protein kinase Nek2

1

11

High-throughput

0.656

High

905289

1433G
14-3-3 protein gamma

3

20

High-throughput

0.650

High

982648

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

48887

POTB3
POTE ankyrin domain family member B3

2

20

High-throughput

0.637

High

1342961

MED4
Mediator of RNA polymerase II transcription subunit 4

2

2

High-throughput

0.635

High

206440

LTOR5
Ragulator complex protein LAMTOR5

2

1

High-throughput

0.632

High

400135

ICAM1
Intercellular adhesion molecule 1

2

9

High-throughput

0.628

High

929127

SKP1
S-phase kinase-associated protein 1

2

1

High-throughput

0.628

High

1332951

SYNCI
Syncoilin

2

7

High-throughput

0.628

High

1346361

EXOC1
Exocyst complex component 1

2

3

High-throughput

0.628

High

674286

HMOX2
Heme oxygenase 2

2

1

High-throughput

0.620

High

782068

RGS2
Regulator of G-protein signaling 2

2

6

High-throughput

0.620

High

277620

PAK3
Serine/threonine-protein kinase PAK 3

1

13

Small-scale

0.618

High

490040

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

2

Small-scale

0.618

High

545710

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

617173

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

3

Small-scale

0.618

High

665371

EPHA2
Ephrin type-A receptor 2

1

16

Small-scale

0.618

High

665688

EPHB2
Ephrin type-B receptor 2

1

12

Small-scale

0.618

High

726563

ARBK2
G protein-coupled receptor kinase 3

1

10

Small-scale

0.618

High

892692

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

913202

ARF6
ADP-ribosylation factor 6

1

15

Small-scale

0.618

High

950582

ARF1
ADP-ribosylation factor 1

1

14

Small-scale

0.618

High

951478

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1160310

PKN3
Serine/threonine-protein kinase N3

1

12

High-throughput

0.618

High

1183621

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1296770

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1357913

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

9

Small-scale

0.618

High

1377269

NINL
Ninein-like protein

1

7

High-throughput

0.618

High

1377462

NEMO
NF-kappa-B essential modulator

1

12

Small-scale

0.618

High

246064

PFD1
Prefoldin subunit 1

3

1

High-throughput

0.615

High

259662

LIPA4
Liprin-alpha-4

2

7

Small-scale

0.609

High

792112

HD
Huntingtin

1

5

High-throughput

0.586

High

1346486

FBX28
F-box only protein 28

2

1

High-throughput

0.574

High

1349402

TMOD4
Tropomodulin-4

2

5

High-throughput

0.574

High

1377463

PCLO
Protein piccolo

1

14

Small-scale

0.573

High

564752

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.553

High

1172362

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.553

High

1331002

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

1331684

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1018762

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.552

High

147299

TXND9
Thioredoxin domain-containing protein 9

1

3

High-throughput

0.541

High

821909

HSP13
Heat shock 70 kDa protein 13

1

5

High-throughput

0.541

High

153960

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

20

High-throughput

0.536

High

158123

TX1B3
Tax1-binding protein 3

1

20

High-throughput

0.536

High

199219

ZNHI1
Zinc finger HIT domain-containing protein 1

1

1

High-throughput

0.536

High

471676

TFPT
TCF3 fusion partner

1

1

High-throughput

0.536

High

853762

IMA5
Importin subunit alpha-5

1

1

High-throughput

0.536

High

1075477

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

20

High-throughput

0.536

High

1137111

CROCC
Rootletin

1

6

High-throughput

0.536

High

1160611

TM154
Transmembrane protein 154

1

1

High-throughput

0.536

High

1184487

CENPQ
Centromere protein Q

1

1

High-throughput

0.536

High

1232989

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.536

High

1284851

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

1318433

UBXN6
UBX domain-containing protein 6

1

3

High-throughput

0.536

High

1332136

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

255262

LIPA3
Liprin-alpha-3

1

9

Small-scale

0.527

High

259656

LIPA2
Liprin-alpha-2

1

9

Small-scale

0.527

High

869432

HAP1
Huntingtin-associated protein 1

1

3

High-throughput

0.527

High

830119

MA2A2
Alpha-mannosidase 2x

1

0

High-throughput

0.518

High

1158412

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.518

High

126872

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

1077988

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

2

High-throughput

0.508

High

869788

TERF1
Telomeric repeat-binding factor 1

1

4

High-throughput

0.494

High

1319426

WDR33
pre-mRNA 3' end processing protein WDR33

1

9

High-throughput

0.494

High

1108775

INAVA
Innate immunity activator protein

1

1

High-throughput

0.489

High

1331211

SENP3
Sentrin-specific protease 3

1

1

High-throughput

0.489

High

1344319

KLHL1
Kelch-like protein 1

1

2

High-throughput

0.489

High

1174750

CENPU
Centromere protein U

1

0

High-throughput

0.486

High

1350349

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.484

High

881067

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.481

High

229120

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

323340

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

12

High-throughput

0.479

High

340557

PGK1
Phosphoglycerate kinase 1

1

1

Small-scale

0.479

High

385765

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

652666

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

780357

CCNF
Cyclin-F

1

8

High-throughput

0.479

High

863608

COPA
Coatomer subunit alpha

1

4

Small-scale

0.479

High

1020239

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

10

Small-scale

0.479

High

1035640

SMAD4
Mothers against decapentaplegic homolog 4

1

8

High-throughput

0.479

High

1052847

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.479

High

1064870

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1081180

CCDC6
Coiled-coil domain-containing protein 6

1

9

High-throughput

0.479

High

1163915

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1168873

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1189078

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1224670

R113B
RING finger protein 113B

1

2

High-throughput

0.479

High

1236590

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.479

High

1281499

FBXW7
F-box/WD repeat-containing protein 7

1

8

High-throughput

0.479

High

1296967

SNX27
Sorting nexin-27

1

20

High-throughput

0.479

High

1310234

LZTS2
Leucine zipper putative tumor suppressor 2

1

16

High-throughput

0.479

High

1319232

GRIP2
Glutamate receptor-interacting protein 2

1

20

Small-scale

0.479

High

1336173

NCK5L
Nck-associated protein 5-like

1

3

High-throughput

0.479

High

1355982

HOOK1
Protein Hook homolog 1

1

5

High-throughput

0.479

High

1357513

SNX6
Sorting nexin-6

1

4

Small-scale

0.479

High

842404

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

1032283

CENPR
Centromere protein R

1

1

High-throughput

0.457

High

1326040

NDEL1
Nuclear distribution protein nudE-like 1

1

11

High-throughput

0.457

High

1344858

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

497850

TAU
Microtubule-associated protein tau

1

18

High-throughput

0.445

High

1302358

CK5P2
CDK5 regulatory subunit-associated protein 2

1

7

High-throughput

0.445

High

166847

ERC2
ERC protein 2

1

6

Small-scale

0.437

High

554109

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

721837

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1270538

HDAC2
Histone deacetylase 2

1

7

High-throughput

0.437

High

1284680

VP33A
Vacuolar protein sorting-associated protein 33A

1

4

High-throughput

0.437

High

886368

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

1333051

CH033
UPF0488 protein C8orf33

2

0

High-throughput

0.323

High

1133145

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.288

High

1315622

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.282

High

1327865

CF263
Cilia- and flagella-associated protein 263

1

0

High-throughput

0.282

High

1314281

FND11
Fibronectin type III domain-containing protein 11

1

0

High-throughput

0.279

Low

1217013

AT2L2
5-phosphohydroxy-L-lysine phospho-lyase

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024