Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: NOTC3 (Q9UM47)
Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain]
Gene: NOTCH3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21502811
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Pkinase, Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 420
Hs

1 2321
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024