HitPredict

Interactor 1: DNLI3 (P49916)
DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)
Gene: LIG3

Interactor 2: TOP3A (Q13472)
DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha)
Gene: TOP3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1009 Hs			1 1001
+	Hs
		328775 DNLI3_HUMAN (1-1009): 0: 1373: 100.00		TOP3B_HUMAN (33-757): 0: 909: 35.13