HitPredict

Interactor 1: GRIA2 (P42262)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	22232691, 11891216, 26472923, 22915106, 25475687, 20802490, 23918399, 24749734
Identification Methods	pull down, two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0030666 - endocytic vesicle membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 883 Hs			1 415
+	Rn
		623693 GRIA2_RAT (1-883): 0: 916: 99.55		PICK1_RAT (1-415): 0: 597: 96.39
+	Mm
		663106 GRIA2_MOUSE (1-883): 0: 917: 99.66		PICK1_MOUSE (1-415): 0: 584: 94.47
+	Rn
		623706 GRIA3_RAT (2-883): 0: 872: 71.57		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		838534 GRIA3_HUMAN (2-883): 0: 874: 71.46		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		838466 GRIA1_HUMAN (4-862): 0: 860: 70.44		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		623728 GRIA4_RAT (1-860): 0: 846: 73.33		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		870110 GRIA4_HUMAN (1-858): 0: 844: 72.57		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		838440 GRIK2_RAT (3-864): 0: 773: 37.81		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		1092406 GRIK2_HUMAN (2-864): 0: 776: 37.88		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		811299 GRIK1_HUMAN (11-880): 0: 754: 36.77		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		652699 GRIK1_RAT (11-853): 0: 742: 37.66		PICK1_RAT (1-415): 0: 597: 96.39