HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	16085932, 19156129, 18715871
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 307
+	Hs
		842815 TCPQ_HUMAN (1-548): 0: 616: 100.00		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		842821 TCPQ_HUMAN (1-548): 0: 616: 100.00		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Mm
		792269 TCPQ_MOUSE (1-548): 0: 617: 96.90		PP1A_MOUSE (2-304): 0: 518: 44.20
+	Hs
		890997 TCPH_HUMAN (9-538): 0: 564: 26.39		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		826591 TCPG_HUMAN (10-547): 0: 558: 28.21		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		915267 TCPH_HUMAN (9-538): 0: 564: 26.39		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		930969 TCPH_HUMAN (9-538): 0: 564: 26.39		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		826603 TCPG_HUMAN (10-547): 0: 558: 28.21		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		826610 TCPG_HUMAN (10-547): 0: 558: 28.21		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		821143 TCPE_HUMAN (2-524): 0: 535: 29.62		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		843130 TCPD_HUMAN (19-525): 0: 530: 28.24		PP4C_HUMAN (1-307): 0: 536: 100.00
+	Hs
		821154 TCPE_HUMAN (2-524): 0: 535: 29.62		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		821161 TCPE_HUMAN (2-524): 0: 535: 29.62		PP2AA_HUMAN (6-307): 0: 522: 65.89
+	Hs
		843141 TCPD_HUMAN (19-525): 0: 530: 28.24		PP2AB_HUMAN (6-307): 0: 523: 65.23
+	Hs
		135404 TCPQ_HUMAN (1-548): 0: 616: 100.00		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Hs
		135491 TCPH_HUMAN (9-538): 0: 564: 26.39		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Hs
		135401 TCPG_HUMAN (10-547): 0: 558: 28.21		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Sc
		618781 TCPH_YEAST (7-542): 0: 534: 28.34		PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98
+	Hs
		135397 TCPE_HUMAN (2-524): 0: 535: 29.62		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92
+	Hs
		135405 TCPD_HUMAN (19-525): 0: 530: 28.24		PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92