HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	16189514, 34133714, 31515488
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 435
+	Hs
		844223 FXR2_HUMAN (1-673): 0: 1004: 100.00		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		843837 FXR1_HUMAN (14-673): 0: 798: 51.34		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		843885 FXR1_HUMAN (14-673): 0: 798: 51.34		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Mm
		1142869 FXR1_MOUSE (14-673): 0: 981: 62.83		STON2_MOUSE (146-433): 1.11e-60: 213: 22.85
+	Hs
		989049 FMR1_HUMAN (310-475): 6.11e-45: 172: 41.42		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00