HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26496610, 31871319
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030667 - secretory granule membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 191
+	Hs
		918847 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		918849 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		925600 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		545307 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		893872 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		900355 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		894409 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		900882 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436244 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		436498 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Zm
		73944 B4FAE1_MAIZE (1-206): 1.49e-87: 258: 33.98		B4FAE1_MAIZE (4-187): 1.98e-74: 224: 25.95
+	Hs
		844863 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		892305 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564470 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		545270 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		844849 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		844856 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436210 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		844848 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564453 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84