Protein: EAA2
Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2)

Gene: EAA2, SLC1A2
Organism: Homo sapiens
Interactions: 101
UniProt ID: P43004

Gene Ontology (top 5):
GO:0005313 - L-glutamate transmembrane transporter activity
GO:0005314 - high-affinity L-glutamate transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006750 - glutathione biosynthetic process
GO:0006811 - monoatomic ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

529280

TAU
Microtubule-associated protein tau

2

6

Small-scale

0.634

High

844953

AJUBA
LIM domain-containing protein ajuba

1

2

Small-scale

0.573

High

844920

GRB2
Growth factor receptor-bound protein 2

1

2

High-throughput

0.541

High

467399

4F2
Amino acid transporter heavy chain SLC3A2

1

1

Small-scale

0.479

High

843356

HD
Huntingtin

1

3

High-throughput

0.470

High

127017

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.445

High

170489

RAB7L
Ras-related protein Rab-7L1

1

12

High-throughput

0.445

High

178537

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

4

High-throughput

0.445

High

228067

PM34
Peroxisomal membrane protein PMP34

1

6

High-throughput

0.445

High

488736

FURIN
Furin

1

3

High-throughput

0.445

High

522615

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

4

High-throughput

0.445

High

749597

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

5

High-throughput

0.445

High

844911

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

1

High-throughput

0.445

High

844913

DGKE
Diacylglycerol kinase epsilon

1

1

High-throughput

0.445

High

844918

RAB38
Ras-related protein Rab-38

1

6

High-throughput

0.445

High

844921

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.445

High

844924

TRAF2
TNF receptor-associated factor 2

1

4

High-throughput

0.445

High

844925

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.445

High

844927

RAB31
Ras-related protein Rab-31

1

9

High-throughput

0.445

High

844928

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.445

High

844935

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.445

High

844936

TSH3
Teashirt homolog 3

1

3

High-throughput

0.445

High

844937

MBOA5
Lysophospholipid acyltransferase 5

1

2

High-throughput

0.445

High

844939

NFXL1
NF-X1-type zinc finger protein NFXL1

1

2

High-throughput

0.445

High

844943

GHDC
GH3 domain-containing protein

1

1

High-throughput

0.445

High

844946

GDPD1
Lysophospholipase D GDPD1

1

1

High-throughput

0.445

High

844948

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

1

High-throughput

0.445

High

844951

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

3

High-throughput

0.445

High

844952

RAB24
Ras-related protein Rab-24

1

9

High-throughput

0.445

High

844954

ZBED3
Zinc finger BED domain-containing protein 3

1

1

High-throughput

0.445

High

844956

DNJC1
DnaJ homolog subfamily C member 1

1

1

High-throughput

0.445

High

844957

F210A
Protein FAM210A

1

1

High-throughput

0.445

High

844959

SORT
Sortilin

1

1

High-throughput

0.445

High

844967

RAB34
Ras-related protein Rab-34

1

7

High-throughput

0.445

High

844972

WDR6
tRNA

1

5

High-throughput

0.445

High

844984

RN114
E3 ubiquitin-protein ligase RNF114

1

3

High-throughput

0.445

High

105508

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

713926

PML
Protein PML

1

5

Small-scale

0.437

High

245436

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.426

High

573371

ENPL
Endoplasmin

1

0

High-throughput

0.426

High

651763

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.426

High

844910

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.426

High

844912

SERPH
Serpin H1

1

0

High-throughput

0.426

High

844914

HXK2
Hexokinase-2

1

0

High-throughput

0.426

High

844919

SMS
Somatostatin

1

0

Small-scale

0.426

High

844922

FOLC
Folylpolyglutamate synthase, mitochondrial

1

0

High-throughput

0.426

High

844930

AMOT
Angiomotin

1

0

High-throughput

0.426

High

844932

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.426

High

844942

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

1

0

High-throughput

0.426

High

844944

PAR16
Protein mono-ADP-ribosyltransferase PARP16

1

0

High-throughput

0.426

High

844966

CA043
Protein C1orf43

1

0

High-throughput

0.426

High

844973

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

844975

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

1

0

High-throughput

0.426

High

122594

UBXN8
UBX domain-containing protein 8

1

1

High-throughput

0.407

High

229420

IDH3B
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

1

2

High-throughput

0.407

High

297052

DHRS3
Short-chain dehydrogenase/reductase 3

1

3

High-throughput

0.407

High

344884

WIZ
Protein Wiz

1

4

High-throughput

0.407

High

451127

NFL
Neurofilament light polypeptide

1

1

High-throughput

0.407

High

844916

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

4

High-throughput

0.407

High

844923

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

1

High-throughput

0.407

High

844926

BIRC2
Baculoviral IAP repeat-containing protein 2

1

2

High-throughput

0.407

High

844929

DPOD3
DNA polymerase delta subunit 3

1

2

High-throughput

0.407

High

844931

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.407

High

844933

P5CR3
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.407

High

844934

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

1

High-throughput

0.407

High

844938

MIC27
MICOS complex subunit MIC27

1

2

High-throughput

0.407

High

844940

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

2

High-throughput

0.407

High

844941

FOXP4
Forkhead box protein P4

1

2

High-throughput

0.407

High

844947

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.407

High

844949

COQ8A
Atypical kinase COQ8A, mitochondrial

1

3

High-throughput

0.407

High

844950

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

1

High-throughput

0.407

High

844955

SRAC1
Protein SERAC1

1

3

High-throughput

0.407

High

844960

CYBC1
Cytochrome b-245 chaperone 1

1

1

High-throughput

0.407

High

844962

ODC
Mitochondrial 2-oxodicarboxylate carrier

1

5

High-throughput

0.407

High

844964

S2533
Solute carrier family 25 member 33

1

6

High-throughput

0.407

High

844971

NEK6
Serine/threonine-protein kinase Nek6

1

3

High-throughput

0.407

High

844976

TV23B
Golgi apparatus membrane protein TVP23 homolog B

1

1

High-throughput

0.407

High

844979

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

1

High-throughput

0.407

High

844983

SALL2
Sal-like protein 2

1

2

High-throughput

0.407

High

162093

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.232

Low

168077

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.232

Low

168973

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.232

Low

257537

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

0

High-throughput

0.232

Low

296210

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.232

Low

516941

GAL3A
Glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial

1

0

High-throughput

0.232

Low

844915

ATP68
ATP synthase F(0) complex subunit j, mitochondrial

1

0

High-throughput

0.232

Low

844917

TMM33
Transmembrane protein 33

1

0

High-throughput

0.232

Low

844945

ARF
Tumor suppressor ARF

1

0

High-throughput

0.232

Low

844958

NSUN5
28S rRNA

1

0

High-throughput

0.232

Low

844961

ANKMT
Adenine nucleotide translocase lysine N-methyltransferase

1

0

High-throughput

0.232

Low

844963

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.232

Low

844965

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

844968

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.232

Low

844969

SNX25
Sorting nexin-25

1

0

High-throughput

0.232

Low

844970

TFB2M
Dimethyladenosine transferase 2, mitochondrial

1

0

High-throughput

0.232

Low

844974

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.232

Low

844977

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.232

Low

844978

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

0

High-throughput

0.232

Low

844980

TDRKH
Tudor and KH domain-containing protein

1

0

High-throughput

0.232

Low

844981

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.232

Low

844982

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025