Protein: FBW1A
F-box/WD repeat-containing protein 1A (Beta-TrCP protein E3RS-IkappaB) (Beta-transducin repeat-containing protein) (Beta-TrCP) (E3RSIkappaB) (mE3RS-IkappaB) (F-box and WD repeats protein beta-TrCP) (HOS) (Ubiquitin ligase FWD1) (pIkappaB-E3 receptor subunit)

Gene: FBW1A, Btrc
Organism: Mus musculus
Interactions: 66
UniProt ID: Q3ULA2

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1190510

SKP1
S-phase kinase-associated protein 1

6

20

Small-scale

0.951

High

1190513

IKBA
NF-kappa-B inhibitor alpha

4

20

Small-scale

0.893

High

1190511

CUL1
Cullin-1

3

20

Small-scale

0.830

High

871189

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

1

Small-scale

0.724

High

236751

PER2
Period circadian protein homolog 2

3

13

Small-scale

0.656

High

1190485

NF2L2
Nuclear factor erythroid 2-related factor 2

2

17

Small-scale

0.643

High

236658

IKBE
NF-kappa-B inhibitor epsilon

1

20

Small-scale

0.618

High

913628

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

5

Small-scale

0.618

High

1190480

FBW1A
F-box/WD repeat-containing protein 1A

1

17

High-throughput

0.618

High

1190484

IKBB
NF-kappa-B inhibitor beta

1

20

Small-scale

0.618

High

1190491

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

8

High-throughput

0.618

High

1190509

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

20

Small-scale

0.618

High

1190514

DX39B
Spliceosome RNA helicase Ddx39b

1

17

High-throughput

0.618

High

204520

PKD2
Polycystin-2

1

1

Small-scale

0.561

High

1081838

GLI2
Zinc finger protein GLI2

1

9

Small-scale

0.561

High

205748

PER1
Period circadian protein homolog 1

1

13

Small-scale

0.536

High

719287

MPIP2
M-phase inducer phosphatase 2

1

7

Small-scale

0.501

High

98026

ACACB
Acetyl-CoA carboxylase 2

1

14

High-throughput

0.479

High

108663

G3X9H5
Huntingtin

1

1

Small-scale

0.479

High

148172

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

204225

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

20

Small-scale

0.479

High

204745

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

11

High-throughput

0.479

High

205385

NUDC
Nuclear migration protein nudC

1

12

High-throughput

0.479

High

236683

B2L11
Bcl-2-like protein 11

1

2

Small-scale

0.479

High

312148

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

14

Small-scale

0.479

High

569699

RL27A
Large ribosomal subunit protein uL15

1

7

High-throughput

0.479

High

578746

GLNA
Glutamine synthetase

1

1

High-throughput

0.479

High

844157

HD
Huntingtin

1

1

Small-scale

0.479

High

958746

CSN2
COP9 signalosome complex subunit 2

1

4

Small-scale

0.479

High

1021500

SMAD4
Mothers against decapentaplegic homolog 4

1

5

Small-scale

0.479

High

1036055

CTNB1
Catenin beta-1

1

18

Small-scale

0.479

High

1190326

Q3UJF1
Histone deacetylase

1

15

High-throughput

0.479

High

1190482

ACACA
Acetyl-CoA carboxylase 1

1

14

High-throughput

0.479

High

1190486

NACA
Nascent polypeptide-associated complex subunit alpha

1

2

High-throughput

0.479

High

1190487

TS101
Tumor susceptibility gene 101 protein

1

1

High-throughput

0.479

High

1190488

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

Small-scale

0.479

High

1190493

Q8BGR3
Calcium/calmodulin-dependent protein kinase type IV

1

1

High-throughput

0.479

High

1190498

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

2

Small-scale

0.479

High

1190500

Q99K94
Signal transducer and activator of transcription

1

4

Small-scale

0.479

High

1190501

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

15

Small-scale

0.479

High

1190503

NSF1C
NSFL1 cofactor p47

1

2

High-throughput

0.479

High

1190504

TP8L2
Tumor necrosis factor alpha-induced protein 8-like protein 2

1

1

Small-scale

0.479

High

1190506

WWTR1
WW domain-containing transcription regulator protein 1

1

16

Small-scale

0.479

High

59707

TPX2
Targeting protein for Xklp2

1

0

Small-scale

0.458

High

1190494

BOLA2
BolA-like protein 2

1

0

High-throughput

0.458

High

1190497

ASGL1
Isoaspartyl peptidase/L-asparaginase

1

0

High-throughput

0.458

High

1190505

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.458

High

1190507

ELP4
Elongator complex protein 4

1

0

High-throughput

0.458

High

1190508

KC1E
Casein kinase I isoform epsilon

1

15

High-throughput

0.457

High

1190512

GSK3B
Glycogen synthase kinase-3 beta

1

11

High-throughput

0.457

High

1190515

HDAC5
Histone deacetylase 5

1

15

High-throughput

0.445

High

1021800

NKX32
Homeobox protein Nkx-3.2

1

8

Small-scale

0.437

High

1064401

PRLR
Prolactin receptor

1

6

Small-scale

0.437

High

1190481

TBC24
TBC1 domain family member 24

1

1

High-throughput

0.437

High

1190483

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

4

High-throughput

0.437

High

1190489

CH10
10 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.437

High

1190490

PPR29
Protein phosphatase 1 regulatory subunit 29

1

1

High-throughput

0.437

High

1190492

RT07
Small ribosomal subunit protein uS7m

1

6

High-throughput

0.437

High

1190495

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

1

High-throughput

0.437

High

1190496

CPNE4
Copine-4

1

1

High-throughput

0.437

High

1190499

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

1

2

High-throughput

0.437

High

1190502

BHE41
Class E basic helix-loop-helix protein 41

1

7

High-throughput

0.417

High

50994

MPEG1
Macrophage-expressed gene 1 protein

1

0

Small-scale

0.249

Low

845179

EAA2
Excitatory amino acid transporter 2

1

0

High-throughput

0.249

Low

845949

LIT1
Lithostathine-1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025