Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1
Interactor 2: DYHC1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)
Gene: DYNC1H1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.979 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 11889140, 35271311, 36692009, 37322240, 27173435, 34079125, 32341549, 37689310, 19622634, 12885786 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, pull down, two hybrid, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AAA_8~WD40, AAA_9~WD40, DHC_N1~WD40, MT~WD40 |
| Common GO terms | GO:0005813 - centrosome GO:0005829 - cytosol GO:0005881 - cytoplasmic microtubule GO:0005938 - cell cortex GO:0007097 - nuclear migration and 4 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
