Protein: SIAS
Sialic acid synthase (N-acetylneuraminate synthase) (EC 2.5.1.56) (N-acetylneuraminate-9-phosphate synthase) (EC 2.5.1.57) (N-acetylneuraminic acid phosphate synthase) (N-acetylneuraminic acid synthase)

Gene: SIAS, NANS
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q9NR45

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006055 - CMP-N-acetylneuraminate biosynthetic process
GO:0008781 - N-acylneuraminate cytidylyltransferase activity
GO:0016051 - carbohydrate biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

497645

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.547

High

211068

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

1

High-throughput

0.541

High

438554

HS90B
Heat shock protein HSP 90-beta

1

1

Small-scale

0.536

High

160798

AURKA
Aurora kinase A

1

0

High-throughput

0.518

High

237521

TLR2
Toll-like receptor 2

1

0

High-throughput

0.518

High

330289

BCL10
B-cell lymphoma/leukemia 10

1

0

High-throughput

0.518

High

339022

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.518

High

516218

DCOR
Ornithine decarboxylase

1

0

High-throughput

0.518

High

522214

CADH1
Cadherin-1

1

0

High-throughput

0.518

High

523167

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.518

High

617677

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.518

High

626259

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

716783

CTNA1
Catenin alpha-1

1

0

High-throughput

0.518

High

855561

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.518

High

1020116

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

0

High-throughput

0.518

High

1079162

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.518

High

1244373

FLCN
Folliculin

1

0

High-throughput

0.518

High

1281413

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.518

High

197409

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.513

High

275291

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

296383

AL1A2
Retinal dehydrogenase 2

1

0

High-throughput

0.513

High

521397

SKIL
Ski-like protein

1

0

High-throughput

0.513

High

670804

BLVRB
Flavin reductase

1

0

High-throughput

0.513

High

902285

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.513

High

1035012

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.513

High

1344250

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

432289

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.479

High

905456

RRAS2
Ras-related protein R-Ras2

1

1

High-throughput

0.479

High

1082410

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.479

High

228804

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

324637

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

337130

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

347987

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

417769

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

444939

ANXA5
Annexin A5

1

0

High-throughput

0.458

High

533348

PLST
Plastin-3

1

0

High-throughput

0.458

High

570097

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

896548

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

1069336

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

1081415

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1163874

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1171865

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1183037

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.458

High

1234388

WDTC1
WD and tetratricopeptide repeats protein 1

1

0

High-throughput

0.458

High

1291712

BICD1
Protein bicaudal D homolog 1

1

0

High-throughput

0.458

High

1344246

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1344248

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

1344249

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.458

High

1069596

PGFRL
Platelet-derived growth factor receptor-like protein

1

0

High-throughput

0.282

High

1344247

MLH3
DNA mismatch repair protein Mlh3

1

0

High-throughput

0.282

High

306428

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low

1314392

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.279

Low

244983

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

329964

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

385573

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

553813

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

600679

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.249

Low

652346

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

721539

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1020579

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.249

Low

1318861

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024