HitPredict

Interactor 1: CDK1 (P43063)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 2)
Gene: CDC28

Interactor 2: HSP90 (P46598)
Heat shock protein 90 homolog
Gene: HSP90

Species: Candida albicans SC5314

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22090345
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 317 Ca			1 707
+	Hs
		468087 CDK2_HUMAN (4-298): 1.19e-155: 438: 64.41		HS90B_HUMAN (8-707): 0: 997: 61.26
+	Hs
		461165 CDK2_HUMAN (4-298): 1.19e-155: 438: 64.41		HS90A_HUMAN (1-707): 0: 995: 61.33
+	Hs
		468267 CDK3_HUMAN (4-299): 1.27e-146: 416: 65.54		HS90B_HUMAN (8-707): 0: 997: 61.26
+	Hs
		461361 CDK3_HUMAN (4-299): 1.27e-146: 416: 65.54		HS90A_HUMAN (1-707): 0: 995: 61.33
+	Hs
		443124 CDK1_HUMAN (4-297): 2.61e-141: 402: 63.95		HS90A_HUMAN (1-707): 0: 995: 61.33
+	Hs
		468269 CDK5_HUMAN (4-298): 4.89e-134: 383: 55.41		HS90B_HUMAN (8-707): 0: 997: 61.26
+	Hs
		461363 CDK5_HUMAN (4-298): 4.89e-134: 383: 55.41		HS90A_HUMAN (1-707): 0: 995: 61.33
+	Sc
		364205 CDK1_YEAST (3-294): 1.56e-135: 387: 78.91		HSP82_YEAST (6-707): 0: 923: 82.20
+	Sc
		364300 CDK1_YEAST (3-294): 1.56e-135: 387: 78.91		HSC82_YEAST (7-707): 0: 922: 83.22
+	Sp
		410445 CDK1_SCHPO (4-296): 2.16e-133: 382: 65.89		HSP90_SCHPO (4-707): 0: 926: 72.91
+	Hs
		573334 CDK2_HUMAN (4-298): 1.19e-155: 438: 64.41		ENPL_HUMAN (4-680): 0: 870: 47.03
+	Sc
		392181 PHO85_YEAST (1-295): 9.71e-126: 363: 51.82		HSP82_YEAST (6-707): 0: 923: 82.20
+	Sc
		578789 PHO85_YEAST (1-295): 9.71e-126: 363: 51.82		HSC82_YEAST (7-707): 0: 922: 83.22