HitPredict

Interactor 1: RORG (P51450)
Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Nuclear receptor subfamily 1 group F member 3) (RAR-related orphan receptor C) (Retinoid-related orphan receptor-gamma) (Thymus orphan receptor) (TOR)
Gene: Rorc

Interactor 2: CUL3 (Q9JLV5)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23086144
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 516 Mm			1 768
+	Hs
		1041596 NR1D2_HUMAN (1-486): 2.45e-106: 331: 28.16		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		846411 RORG_HUMAN (1-516): 3.56e-148: 436: 88.61		CUL4B_HUMAN (5-768): 0: 795: 36.77
+	Hs
		509948 VDR_HUMAN (14-508): 6.1e-70: 231: 17.69		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		823983 NR2C2_HUMAN (10-501): 2.52e-103: 323: 18.94		CUL4A_HUMAN (10-768): 0: 801: 38.45
+	Hs
		823984 NR2C2_HUMAN (10-501): 2.52e-103: 323: 18.94		CUL4B_HUMAN (5-768): 0: 795: 36.77
+	Hs
		622792 COT2_HUMAN (25-110): 1.39e-26: 113: 58.14		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		1030586 STF1_HUMAN (24-506): 8.95e-83: 266: 20.36		CUL4B_HUMAN (5-768): 0: 795: 36.77
+	Hs
		659714 RXRB_HUMAN (31-111): 2.94e-24: 108: 55.56		CUL3_HUMAN (1-768): 0: 952: 99.48
+	Hs
		818874 RXRG_HUMAN (19-216): 1.06e-48: 176: 28.79		CUL1_HUMAN (18-768): 0: 707: 29.94
+	Dm
		709190 ECR_DROME (11-511): 2.86e-77: 261: 20.28		Q9V9R2_DROME (30-768): 0: 610: 24.39