Interactor 1: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Interactor 2: DMC1 (Q14565)
Meiotic recombination protein DMC1/LIM15 homolog
Gene: DMC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 26976601, 20729832, 17541404
Identification Methods pull down, affinity chromatography technology, two hybrid, unspecified method, anti bait coimmunoprecipitation, filter binding, competition binding, peptide array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCA2~Rad51
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000800 - lateral element
GO:0001556 - oocyte maturation
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 3418
Hs

1 340
+ Hs
+ Hs
+ Hs
+ Cl
+ Mm
+ Mm
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024